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Total number of cancer cells reflects prognosis.
2004 DEC 2 - (NewsRx.com & NewsRx.net) -- A study from Japan says the total number of breast cancer cells in cancerous tissue reflects the patient's prognosis.
"Ninety-three cases of both invasive ductal and lobular carcinoma were examined to clarify the relationship between the clinicopathological factors and cellularity (cell density) or total cancer cells number in carcinoma tissues," reported K. Tanaka and colleagues, Kansai Medical University.
"The cellularity showed significant correlation with tumor size and vascular invasion, but not with other clinicopathological factors (menopausal status, operation method, estrogen receptor status, histological grade or type, lymph node stage) and prognosis," they said.
"The total cancer cell number revealed a positive relationship with survival (overall survival) and disease-free interval by univariate analysis, even though it did not show any positive correlation with other clinicopathological factors in this study," the researchers wrote.
"Moreover, it was not found to have any stronger impact than other previously reported prognostic factors such as tumor size, ...
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Source: HighBeam Research, Total number of cancer cells reflects prognosis.