AccessMyLibrary provides FREE access to over 30 million articles from top publications available through your library.
Create a link to this page
Copy and paste this link tag into your Web page or blog:
Serum sex hormones associated with increased cancer risk in younger women.
2004 DEC 2 - (NewsRx.com & NewsRx.net) -- Ovarian hyperandrogenism associated with luteal insufficiency increases the premenopausal women's risk of developing breast cancer, researchers in Italy report.
"Because of large intra-individual variation in hormone levels, few studies have investigated the relation of serum sex hormones to breast cancer (BC) in premenopausal women. We prospectively studied this relation, adjusting for timing of blood sampling within menstrual cycle," said A. Micheli and colleagues.
"Premenopausal women (n=5,963), recruited to the Hormones and Diet in the Etiology of Breast Tumors (ORDET) cohort study, provided a blood sample in the 20-24th day of their menstrual cycle. After 5.2 years of follow-up, 65 histologically confirmed BC cases were identified and matched individually to four randomly selected controls," the researchers said.
They had levels of the following hormones measured blindly from serum samples stored at -80 degrees C: for dehydroepiandrosterone sulfate; total and free testosterone (FT); androstenedione; androstanediol-glucoronide; progesterone; 17-OH-progesterone; sex hormone-binding globulin; follicle-stimulating hormone (FSH); and luteinizing hormone (LH).
Multivariate analyses could be performed on 55 of the 65 cases.
"Compared to controls, BC cases had shorter cycles and intervals between blood sampling and bleeding, and lower LH and FSH," according to the report.
Micheli and colleagues found "FT was significantly ...
- The specific role of isoflavones on estrogen metabolism in premenopausal...
- Magazine article from: Alternative Medicine Review Kumar, NB Cantor, A Allen, K June 1, 2002 700+ words
...in the production, metabolism, and bioavailability of sex hormones and their impact on target tissues. The specific objective...evaluate the effectiveness of supplementing a group of premenopausal women who were free of breast carcinoma with a dietary supplement...
- Low bone mineral density in premenopausal women.(Featured CME Topic:...
- Magazine article from: Southern Medical Journal Lewiecki, E. Michael June 1, 2004 700+ words
...an increasing number of premenopausal women are having their bone density...Approximately 15% of premenopausal women have bone mineral density...mean bone density. Most premenopausal women with low bone density have...
- Low estrogen linked to increased risk of CAD in premenopausal women.
- Newspaper article from: Heart Disease Weekly March 2, 2003 700+ words
...disease is the leading killer of premenopausal women, taking even more lives than breast...we're seeing that even young, premenopausal women lose protection from coronary artery...and coronary artery disease in premenopausal women, statistics on 95 women were analyzed...
- Low estrogen linked to increased risk of CAD in premenopausal women.(coronary...
- Magazine article from: Women's Health Weekly February 27, 2003 700+ words
...disease is the leading killer of premenopausal women, taking even more lives than breast...we're seeing that even young, premenopausal women lose protection from coronary artery...and coronary artery disease in premenopausal women, statistics on 95 women were analyzed...
- Insulin sensitivity linked to visceral fat mass in premenopausal women.
- Newspaper article from: Obesity, Fitness & Wellness Week February 8, 2003 700+ words
...fat mass and insulin resistance in premenopausal women, according to a report in the Journal...composition in 40 abdominally obese, premenopausal women. The women underwent measurements...composition, and insulin resistance in premenopausal women. Journal of Clinical Endocrinology...
- Calcaneal ultrasound helps identify premenopausal women at risk for bone loss.
- Newspaper article from: OBGYN & Reproduction Week June 21, 2004 700+ words
...quantitative ultrasound (QUS) in premenopausal women. The study cohort was a subsample of 2,727 premenopausal women participating in the ''Epidemiological...stiffness, as measured by QUS in premenopausal women. These findings should help...
- United States: Screening, treatment of osteoporosis in premenopausal women...
- News wire article from: TendersInfo October 14, 2009 700+ words
...suggests that a higher percentage of premenopausal women than previously reported may have...University in New York evaluated 61 premenopausal women at an osteoporosis referral center...identifiable. It is important to evaluate premenopausal women for secondary causes of ...
- Postmenopausal Women With Osteoporosis Treated With Actonel for Five Years Have...
- Press release article from: PR Newswire October 4, 2004 700+ words
...at levels comparable to those of premenopausal women. Mineralization is a property of...state similar to that of healthy premenopausal women." Bone is a living tissue. Older...was comparable to that of healthy premenopausal women, and it remained at a steady level...
Source: HighBeam Research, Serum sex hormones associated with increased cancer risk in younger...