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2004 DEC 2 - (NewsRx.com & NewsRx.net) -- Researchers have investigated the effect of atrial pressure increase on sinus node automaticity
"There is evidence suggesting that atrial electrophysiological properties may be changed by an acute increase in atrial pressure. The aim of [our]study was to investigate the effect of alteration in atrial pressure on sinus node recovery time," scientists in Greece report.
M. Efremidis and colleagues of "Evangelismos" General Hospital in Athens described their study, "Twelve patients (8 men and 4 women, mean age 61.3[+ or -]14.1 years) were included in this study. None of the patients had organic heart disease. Sinus node recovery time (SNRT) was measured following atrial pacing and atrioventricular (AV) pacing at sequential cycle lengths of 600, 545, 500, 461, 428, and 400 ms with two different AV intervals (150, 0 ms)."
"Peak and minimal atrial pressure increased significantly from 8.5[+ or -]2.8 to 20.1[+ or -]2.9 mmHg (11.56[+ or -]3.8 to 27.3[+ or -]3.9 cmH[subscript]2O) (P=0.001) and from 2.06[+ or -]1.69 to 5.33[+ or -]2.9 mmHg (2.8[+ or -]2.29 to 7.2[+ or -]3.9 ...
Source: HighBeam Research, Atrial pressure increase does not significantly affect sinus node...