AccessMyLibrary provides FREE access to over 30 million articles from top publications available through your library.
Create a link to this page
Copy and paste this link tag into your Web page or blog:
Suppressed E1AF limits the invasiveness of cervical cancer.
2004 DEC 2 - (NewsRx.com & NewsRx.net) -- Suppressed E1AF limits the invasiveness of cervical cancer.
According to a study from Japan, "E1AF/PEA3, a member of the Ets family of transcription factors, is associated with the malignant characteristics of cancer cells. The initial aim of our study was to test whether the invasiveness of SiHa cervical cancer cells could be diminished by transfection with antisense E1AF. Using an in vitro invasion assay in which cells penetrate a layer of Matrigel, we found that this was not the case; indeed, the invasiveness of the transfectants was enhanced."
"To better understand the mechanism of this enhancement, we used the cDNA microarray technique to search for genes whose expression was altered in the antisense E1AF-transfected SiHa cells. Among several genes affected, we found that expression of squamous cell carcinoma antigen (SCCA), a member of the ovalbumin serine proteinase inhibitor family, was significantly reduced," wrote M. Iwasaki and colleagues, Sapporo Medical University, Department of Obstetrics and Gynecology.
"Forced expression of E1AF enabled activation of SCCA expression, and luciferase reporter assays revealed that E1AF activates the SCCA promoter. Introduction of antisense SCCA into SiHa cells inhibited ...
- Cervical Cancer - NCCPP Urges Qiagen to Extend Digene HPV Test Kit.
- Newspaper article from: Vanguard (Nigeria) June 16, 2009 700+ words
...the national cervical cancer screening programme...available to Good Health Weekly, noted that...hospital records, cervical cancer kills one Nigerian...have ever had cervical cancer screening in...lifetime. Good Health Weekly reported exclusively...
- Women in Finland with 5+ children have higher risk of cervical cancer.
- Magazine article from: Women's Health Weekly June 24, 2004 700+ words
...risk of developing cervical cancer, their relative...study on the risk of cervical cancer and cervical intraepithelial...of Epidemiology, Cervical Cancer, Risk Factors...prepared by Women's Health Weekly editors from staff...
- A new technique of laparoscopic hysterectomy may be useful in cervical...
- Magazine article from: Women's Health Weekly April 10, 2003 700+ words
...advantage of TLRH for cervical cancer is that the entire...in treating early cervical cancer." Lee and colleagues...subject areas of Cervical Cancer, Surgery and Oncology...prepared by Women's Health Weekly editors from staff...
- Correct HPV diagnosis in men can help prevent cervical cancer in women.
- Magazine article from: Women's Health Weekly June 10, 2004 700+ words
...subsequently can cause cervical cancer. "The increasing...the prevention of cervical cancer," Aynaud and colleagues...Papillomavirus, Cervical Cancer, Sexually Transmitted...prepared by Women's Health Weekly editors from staff...
- P73 A4T14 genotype associated with cervical cancer risk.
- Magazine article from: Women's Health Weekly May 6, 2004 700+ words
...variant and the risk of cervical cancer in" a "Japanese...Arg72Pro and the risk of cervical cancer in Japanese. Cancer...Factor, Genomics, Cervical Cancer and Women's Health...prepared by Women's Health Weekly editors from staff...
- Novel human gene homologue found associated with cervical cancer.
- Magazine article from: Women's Health Weekly July 22, 2004 700+ words
...significant role in cervical cancer, researchers say...expressed in uterine cervical cancer, with weak expression...Cancer Genetics, Cervical Cancer, and Women's Health...prepared by Women's Health Weekly editors from staff...
- DNA image cytometry used to diagnose cervical cancer.
- Magazine article from: Women's Health Weekly June 17, 2004 700+ words
...diagnosis and prognosis of cervical cancer. "In the fight against...major subject areas of Cervical Cancer, Diagnostics, Oncology, Cervical Cancer Prognosis, and Women...prepared by Women's Health Weekly editors from staff and...
- American Cancer Society issues new early detection guidelines.(for cervical...
- Magazine article from: Women's Health Weekly December 12, 2002 700+ words
...cervix should continue cervical cancer screening at least...in detecting early cervical cancer in women over 30...early detection of cervical cancer to develop consistent...prepared by Women's Health Weekly editors from staff...
- Adjuvant oral 5-fluorouracil useful for cervical cancer.
- Magazine article from: Women's Health Weekly June 17, 2004 700+ words
...with low-stage cervical cancer who have some risk...fluorouracil for cervical cancer: Japanese Gynecologic...subject areas of Cervical Cancer Therapy, Oncology...prepared by Women's Health Weekly editors from staff...
- Seminal plasma activates enzyme and hormone in cervical cancer cells.
- Magazine article from: Women's Health Weekly February 20, 2003 700+ words
...UK. The information in this article comes under the major subject areas of Cervical Cancer, Enzymology, Gynecology, Obstetrics and Oncology. This article was prepared by Women's Health Weekly editors from staff and other reports.
Source: HighBeam Research, Suppressed E1AF limits the invasiveness of cervical cancer.