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Study links PCOS with early vascular changes of heart disease.
2004 DEC 2 - (NewsRx.com & NewsRx.net) -- Polycystic ovary syndrome (PCOS), a disorder characterized by metabolic and endocrine abnormalities, endangers women's hearts by causing early buildup of calcium in coronary arteries, researchers report.
"Our findings indicate a strong correlation between PCOS, metabolic cardiovascular syndrome, and initial evidence of calcium deposits that signal blood vessel disease," said Evelyn Talbott, DrPH, professor of epidemiology and communication science at the University of Pittsburgh Graduate School of Public Health, and the study's first author. "Given the large number of women with PCOS and the long incubation period for calcium accumulation in coronary arteries, early and aggressive intervention through lifestyle changes and medication may significantly reduce heart disease-related death and illness."
PCOS is a common disorder that affects up to 7% of the female population, or about 10 million women, in the United States. Some estimates are that as many as 10% of reproductive-age women are affected by PCOS. Previously treated on a symptom-by-symptom basis by physicians unaware that a larger and more complicated ailment was present, PCOS today is increasingly being recognized as a lifelong, hereditary, reproductive endocrine condition with physical and emotional consequences. Common symptoms include infertility, irregular menstrual cycles, excess body hair, ovarian cysts, acne, and obesity.
The American Association of Clinical Endocrinologists recently issued a position paper to raise awareness of the disorder, saying that women with PCOS "are at greatest risk for diabetes and coronary artery disease."
Talbott's study involved 61 women with PCOS who underwent noninvasive electron beam tomography scanning of their coronary and abdominal arteries. Results for the 61 women with PCOS were compared with those for control subjects matched for age, race, and body weight, and overall values were compared with recorded baseline measurements taken in 1992 and 1993, an average of 9 years earlier. The heaviest women were ...
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