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VIP/NTM-reactive natural antibodies applied to HIV infection therapy.
2004 DEC 1 - (NewsRx.com & NewsRx.net) -- Researchers have applied VIP/NTM-reactive natural antibodies to HIV infection therapy.
"In sera of HIV-infected individuals natural antibodies recognizing nonimmunogenic C-terminal domain of the second conserved region of HIV-1 gp120 and the vasoactive intestinal peptide (VIP) were identified. It has been demonstrated that these antibodies are significantly more prevalent in asymptomatic carriers than in AIDS patients and that their titer strongly correlates with disease progression," scientists in Yugoslavia report.
"These findings point out the VIP/C2-reactive natural antibodies as an important agent for immunotherapy of HIV disease," wrote Veljko Veljkovic at the Institute of Nuclear Sciences in Yugoslavia and R. Metlas at Diapharm Ltd. in the U.K.
Veljkovic and Metlas published their study in International Reviews ...
- CONNING ANTIBODIES INTO TOLERATING PORCINE ANTIGENS GENE THERAPY DEFUSES...
- Magazine article from: BIOWORLD Today September 18, 1998 700+ words
...response to the antigen." As the endpoint of the experiment, his paper reported, "The level of alpha-Gal-reactive natural antibodies remained undetectable in the mice up to 51 weeks after transplantation." "This is pretty long in the life...
- BioTransplant Collaborators at MGH Report Advances Toward Establishing...
- Press release article from: PR Newswire September 18, 1998 700+ words
...xenografted porcine tissue is caused by natural antibodies, the majority of which are directed...including eliminating the circulating natural antibodies, these antibodies eventually return...gene therapy, the production of natural antibodies in a murine [mouse] model. This...
- Massachusetts General Hospital and BioTransplant Report Research Advances for...
- Press release article from: PR Newswire October 25, 1999 700+ words
...to be sensitive to rejection via natural antibodies, and when transplanted into a primate...least half of the pig-specific natural antibodies in primates. The researchers investigated...or prevent the appearance of these natural antibodies and to promote tolerance to pig xenografts...
- HBsAg variants break tolerance in hepatitis B surface antigen mice.
- Newspaper article from: Drug Week February 20, 2004 700+ words
...com & NewsRx.net) -- Vaccination with cross-reactive, natural HBsAg variants breaks tolerance in hepatitis B surface...antigen (HBsAg) transgenic mice by vaccination with cross-reactive, natural HBsAg variants. Eur J Immunol, 2003;33(12):3342...
- Immunomedics Developing Vaccines for Cancer and Infectious Diseases.
- Press release article from: PR Newswire February 2, 2000 700+ words
...galactose bind to their targets and "coat" them with this receptor for the natural antibodies. "Humans and certain lower primates have these natural antibodies without the alpha-galactose antigen in their systems," explained Dr. Goldenberg...
- The xeno-solution. (animal-to-human organ transplants)(includes related article)
- Magazine article from: Science News Travis, John November 4, 1995 700+ words
...human blood, as well as that of many nonhuman primates, are natural antibodies that view alpha-gal molecules as evidence of a foreign invasion. "The xenoreactive natural antibodies, as soon as blood flows into that organ, will recognize...
- Scientists at Stanford University, Medical Department target Alzheimer disease.
- Newspaper article from: Biotech Business Week September 21, 2009 700+ words
...we demonstrate with peptide microarrays the presence of natural antibodies against known toxic A beta and amyloidogenic non-A beta...Sciences of the United States of America (Neuroprotective natural antibodies to assemblies of amyloidogenic peptides decrease with...
- Research data from Wageningen University update understanding of poultry...
- Newspaper article from: Agriculture Week September 17, 2009 700+ words
...disease and infectious bursal disease vaccines; levels of natural antibodies binding lipopolysaccharide, lipoteichoic acid, and keyhole...significant differences were found in lipoteichoic acid natural antibodies of the control and low line hens. At the end of the observation...
