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Phase II data for HIV drug presented at conference.
2004 DEC 1 - (NewsRx.com & NewsRx.net) -- Ono Pharmaceutical Co., Ltd., announced that a phase II clinical study with a new HIV drug (development code: ONO-4128/873140) has been completed. The results of the study were presented at the 44th Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC).
This agent was licensed by Ono Pharmaceutical to GlaxoSmithKline (GSK) in December 2002.
In the study, ONO-4128/873140 was administered to 40 adult HIV patients as monotherapy for a short period of time to examine its antiviral effect, safety, pharmacokinetics and CCR5 receptor occupancy. Forty adult HIV patients were equally divided into 4 dose groups: once daily dose of 200 mg, twice daily dose of 200 mg, once daily dose of 400 mg, and twice daily dose of 600 mg.
The investigational drug or placebo was administered to the 10 patients of each group (8 and 2 patients, respectively) for 10 days to observe the patients until day 24. The antiviral effect was evaluated with decrease in number of copies of HIV RNA in ...
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- Press release article from: PR Newswire June 5, 1998 700+ words
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- Press release article from: Business Wire April 2, 1998 700+ words
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Source: HighBeam Research, Phase II data for HIV drug presented at conference.