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Formaldehyde-inactivated Japanese encephalitis virus vaccine developed.
2004 DEC 1 - (NewsRx.com & NewsRx.net) -- A formaldehyde-inactivated Indian strain of Japanese encephalitis virus grown in Vero cells
"P20778, an Indian strain of Japanese encephalitis virus (JEV) obtained from Vellore in the Southern India, was grown in Vero cells cultured on microcarriers in a spinner flask. The virus was formalin-inactivated and its immunogenicity and protective efficacy in mice were tested in comparison with a commercially available vaccine. Our studies indicated that formalin-inactivated JEV P20778 induced high levels of protective immunity in mice," researchers in India report.
"Virus inactivation with formalin at 22 degrees C, which required shorter incubation period, was found to be as good or better to virus inactivation at 4 degrees C for generating high titers of anti-JEV antibodies," said Mohan Babu Appaiahgari and Sudhanshu Vrati at the National Institute of Immunology in New Delhi. "Similarly, the 22 degree C-inactivated virus generated JEV neutralizing antibody titers as good or higher than those induced by the 4 degree C-inactivated virus. Thus, for the ...
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- Formaldehyde-inactivated Japanese encephalitis virus vaccine developed.
- Newspaper article from: Virus Weekly November 30, 2004 700+ words
...inactivated Indian strain of Japanese encephalitis virus grown in Vero cells "P20778, an Indian strain of Japanese encephalitis virus (JEV) obtained from...inactivated Indian strain of Japanese encephalitis virus grown in Vero cells...
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Japanese Encephalitis Guirakhoo, F.; Zhang, Z...Recombinant, Chimeric Yellow Fever-Japanese Encephalitis Virus (ChimeriVax-JE) as a Live...Attenuated Vaccine Candidate Against Japanese Encephalitis." Virology, May 10, 1999...
- Japanese encephalitis virus infection is blocked by chlorpromazine.
- Newspaper article from: Immunotherapy Weekly September 10, 2003 700+ words
...NewsRx.net) -- Japanese encephalitis virus infection occurs by clathrin...process. "Entry of Japanese encephalitis virus (JEV) into cells was...Virology (Interference in Japanese encephalitis virus infection of Vero cells...
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- Newspaper article from: Health & Medicine Week August 18, 2003 700+ words
...cytokine immune response to Japanese encephalitis virus inoculation in mice...immunized with live Japanese encephalitis virus (JEV) by intraperitoneal...T helper responses to Japanese encephalitis virus infection are dependent...
