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Research institute announces discovery on the virus' role in autoimmune disease.

Vaccine Weekly

| December 01, 2004 | COPYRIGHT 2004 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

2004 DEC 1 - (NewsRx.com & NewsRx.net) -- Researchers at the La Jolla Institute for Allergy & Immunology announced the addition of a milestone to scientific understanding of the role viruses play in the development of autoimmune diseases, such as diabetes.

Matthias von Herrath, M.D., and a team of scientists found that while viruses alone do not initiate autoimmune diseases, they can accelerate their development when paired with a genetic predisposition to autoimmune diseases.

According to the announcement, this discovery, based on controlled laboratory studies of mice, represents the first demonstration in a living organism of the ability of viruses to increase the likelihood of the development of autoimmune diseases.

The paper, "A Viral Epitope that Mimics a Self Antigen Can Accelerate But Not Initiate Autoimmune Diabetes," was published in the Journal of Clinical Investigation.

von Herrath's research focused on a concept known as "molecular mimicry" or ...

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