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2004 DEC 1 - (NewsRx.com & NewsRx.net) -- Researchers at the La Jolla Institute for Allergy & Immunology announced the addition of a milestone to scientific understanding of the role viruses play in the development of autoimmune diseases, such as diabetes.
Matthias von Herrath, M.D., and a team of scientists found that while viruses alone do not initiate autoimmune diseases, they can accelerate their development when paired with a genetic predisposition to autoimmune diseases.
According to the announcement, this discovery, based on controlled laboratory studies of mice, represents the first demonstration in a living organism of the ability of viruses to increase the likelihood of the development of autoimmune diseases.
The paper, "A Viral Epitope that Mimics a Self Antigen Can Accelerate But Not Initiate Autoimmune Diabetes," was published in the Journal of Clinical Investigation.
von Herrath's research focused on a concept known as "molecular mimicry" or ...