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Investigators awarded grants from U.S. DoD Breast Cancer Research Program.

Vaccine Weekly

| December 01, 2004 | COPYRIGHT 2004 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

2004 DEC 1 - (NewsRx.com & NewsRx.net) -- Five scientific investigators at The Scripps Research Institute were awarded research grants from the U.S. Department of Defense (DoD) Breast Cancer Research Program.

The following awards were made to investigators at Scripps Research as part of this effort:

Ralph A. Reisfeld, PhD, was awarded a DoD Breast Cancer Research Program Idea Award of $563,100 for his proposal, "An Oral DNA Vaccine Encoding Endoglin Eradicates Breast Tumors by Blocking Their Blood Supply." Reisfeld seeks to develop DNA vaccines that will prevent or slow breast cancer metastasis by choking off the blood supply to tumor cells, leading to their starvation and death.

Jiing-Dwan Lee, PhD, was awarded a DoD Breast Cancer Research Program Idea Award of $563,100 for his proposal, "Molecular Action of a Potential Tumor Suppressor in Mammary Carcinogenesis." Lee is investigating how the expression of a human tumor suppressor protein called Tid1 has the ability to suppress the growth of malignant breast cancer tumors.

Roberto G. Baccala, PhD, was awarded a DoD Breast Cancer Research Program Idea Award of $563,100 for his proposal, "Homeostatic T Cell Expansion to Induce Anti-Tumor Autoimmunity in Breast Cancer." Baccala is exploring how to enhance the natural ability of the immune system's T cells to attack and kill breast cancer cells specifically.

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