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Vaccine protects cheetah and black rhinoceros against anthrax.
2004 DEC 1 - (NewsRx.com & NewsRx.net) -- Researchers have developed a vaccine that protects cheetahs and rhinoceroses against anthrax.
According to a study from England, Namibia, and the United States, "Institution of a policy of vaccination in endangered species with a vaccine not previously administered to it cannot be undertaken lightly. This applies even more in the case of cheetah (Acinonyx jubatus) with their unusually monomorphic gene pool and the potential restrictions this places on their immune responses. However, the recently observed mortalities from anthrax in these animals in the Etosha National Park, Namibia, made it imperative to evaluate vaccination. Black rhinoceros (Diceros bicornis), another endangered species in the park, have been vaccinated for over three decades but the effectiveness of this has never been evaluated."
"Passive protection tests in A/J mice using sera from 12 cheetahs together with enzyme immunoassay indicated that cheetah are able to mount seemingly normal primary and secondary humoral immune responses to the Sterne 34F2 live spore livestock vaccine," reported Peter C. B. Turnbull at Arjemptur Technology in England and collaborators in Namibia and the U.S. "Overall protection rates in mice injected with the sera rose and fell in concert with rises and declines in antibody titers, although fine analysis showed that the correlation between titer and protection was complex."
"Once a high level of protection (96% of mice 1 month after a second booster in the cheetahs) had been achieved, the duration of substantial protection appeared good (60% of the mice 5 months after the ...
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Source: HighBeam Research, Vaccine protects cheetah and black rhinoceros against anthrax.