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Neuroscientists awarded $1.1 million grant to improve Alzheimer vaccine.
2004 DEC 1 - (NewsRx.com & NewsRx.net) -- University of South Florida (USF) College of Medicine neuroscientists have been awarded a $1.1 million federal grant to improve the safety and effectiveness of an Alzheimer vaccine in a mouse model.
"This approach shifts the focus from treating symptoms of Alzheimer's disease to treatments that slow down the disease or prevent it altogether," said Jun Tan, MD, PhD, director of the Neuroimmunology Laboratory in the USF department of psychiatry.
Tan is principal investigator for the 4-year grant from the National Institute for Neurological Disorders and Stroke. He will work with co-investigator David Morgan, PhD, director of the Alzheimer's Disease Research Laboratory in the USF department of pharmacology and therapeutics.
The study builds on previous USF laboratory and animal model studies that tracked the role of the brain's immune system in Alzheimer disease. Under certain circumstances, immune cells in the brain, known as microglia, promote the inflammatory and destructive process that can lead to Alzheimer disease.
The USF researchers demonstrated that once a specific molecule on the surface of ...
- Scientists Announce Initial Results of Alzheimer Vaccine Treatment in...
- Newspaper article from: Vaccine Weekly July 26, 2000 700+ words
...are moving closer to identifying an intervention that will be able to alter the course of the disease." This article was prepared by Vaccine Weekly editors from staff and other reports. Copyright 2000, Vaccine Weekly via NewsRx.com.
- Company gets U.S. patent for Alzheimer vaccine.
- Newspaper article from: Vaccine Weekly December 10, 2003 700+ words
...versatile proprietary platform for selection of an ideal therapeutic molecule," said Dr. Daniel Chain, president and CEO of Mindset BioPharmaceuticals. This article was prepared by Vaccine Weekly editors from staff and other reports.
- Late Breakers: Vagal Nerve Stimulation Fails in Depression; Alzheimer Vaccine...
- Newspaper article from: Neurology Alert April 1, 2002 700+ words
...given where polypharmacy is often required but poorly tolerated, it would a valuable addition to depression treatment. An Alzheimer vaccine trial is stopped. Elan Corp and Wyeth-Ayerst Laboratories suspended all trials of the drug AN-1792 after 15 patients...
- ALZHEIMER VACCINE MAY BE MODIFIED\ STUDY: IT MAY BE SAFE FOR HUMANS.(News)
- Newspaper article from: The Cincinnati Post (Cincinnati, OH) October 25, 2002 700+ words
Byline: Associated Press WASHINGTON -- A new study suggests it may be possible to modify an experimental vaccine for Alzheimer's disease, making it safe for humans. The vaccine was withdrawn earlier this year because of side effects in test subjects. A refined form of the vaccine for the
- Report: Elan halts Alzheimer vaccine tests.
- News wire article from: United Press International February 26, 2002 700+ words
WASHINGTON, Feb 22, 2002 Irish drug maker Elan Corp. has halted trials of an experimental Alzheimer's vaccine after 12 volunteers became ill with brain inflammation, The Washington Post reported Friday. The Post quoting sources familiar with the study as saying there was little question the
- Scientists Announce Initial Results of Alzheimer Vaccine Treatment in Humans.
- Press release article from: PR Newswire July 11, 2000 700+ words
Research Confirms Vaccine's Mechanism of Action WASHINGTON, D.C., July 11 /PRNewswire/ -- Initial results of an ongoing phase I clinical trial of a potential vaccine for Alzheimer's disease have shown that the vaccine is well tolerated in humans, according to scientists at Elan Pharmaceuticals, a
- One Step Closer to an Alzheimer Vaccine.(Society)(Brief Article)
- Magazine article from: Newsweek Rainey, Susan July 24, 2000 700+ words
Scientists at the World Alzheimer Congress in Washington, D.C., last week announced preliminary results from studies of a vaccine that may one day help treat or even prevent Alzheimer's, bringing new hope to the 4 million Americans battling the disease. One of the hallmarks of Alzheimer's is
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- Newspaper article from: Vaccine Weekly December 11, 2002 700+ words
...side effects of Alzheimer vaccine therapy. "Up to...human trials of Alzheimer vaccine "were premature...But he said Alzheimer vaccine therapy remains...was prepared by Vaccine Weekly editors from staff...