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Myopericarditis reported following smallpox vaccination.
2004 DEC 1 - (NewsRx.com & NewsRx.net) -- The incidence of myopericarditis following smallpox vaccination was higher than expected.
"Myopericarditis has been a rare or unrecognized event after smallpox vaccinations with the New York City Board of Health strain of vaccinia virus (Dryvax; Wyeth Laboratories, Marietta, Pennsylvania). In this article, the authors report an attributable incidence of at least 140 clinical cases of myopericarditis per million primary smallpox vaccinations with this strain of vaccinia virus. Fifty-eight males and one female aged 21-43 years with confirmed or probable acute myopericarditis were detected following vaccination of 492,730 U.S. Armed Forces personnel from December 15, 2002, through September 30, 2003," investigators in the United States report.
"The cases were identified through sentinel reporting to military headquarters, active surveillance using the Defense Medical Surveillance System, or reports to the Vaccine Adverse Event Reporting System," explained Mark K. Arness of the U.S. Air Force and fellow members of the Department of Defense Smallpox Vaccination Clinical Evaluation Team.
"The observed incidence (16.11/100,000) of myopericarditis over a 30-day observation window among 347,516 primary vaccinees was nearly 7.5-fold higher ...
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