AccessMyLibrary provides FREE access to over 30 million articles from top publications available through your library.
Create a link to this page
Copy and paste this link tag into your Web page or blog:
Immunodominant sites on spike protein of SARS coronavirus identified.
2004 DEC 1 - (NewsRx.com & NewsRx.net) -- Scientists have identified immunodominant sites on the spike protein of severe acute respiratory syndrome (SARS) coronavirus.
"The spike (S) protein of severe acute respiratory syndrome (SARS) coronavirus (SARS-CoV) is not only responsible for receptor binding and virus fusion, but also a major antigen among the SARS-CoV proteins that induces protective antibody responses. In this study, we showed that the S protein of SARS-CoV is highly immunogenic during infection and immunizations, and contains five linear immunodominant sites (sites I to V) as determined by Pepscan analysis with a set of synthetic peptides overlapping the entire S protein sequence against the convalescent sera from SARS patients and antisera from small animals immunized with inactivated SARS-CoV," investigators in the United States and China report.
"Site IV located in the middle region of the S protein (residues 528-635) is a major immunodominant epitope," said Yuxian He at the New York Blood Center in the U.S. and collaborators in the U.S. and China. "The synthetic peptide S[subscript]603-634, which overlaps the site IV sequence reacted with all the convalescent sera from 42 SARS patient, but none of the 30 serum samples from ...
- SARS' impact outlasts disease; Less travel, many winners in New...
- Magazine article from: Crain's New York Business June 23, 2003 700+ words
...marshall When news of Severe Acute Respiratory Syndrome first hit in March...his firm's future work in New York and take advantage of the...pronounced SARS dead, but few of New York's toy, apparel and finance...the language barrier between New York and Asia requires ...
- Acute Respiratory Disease Associated with Adenovirus Serotype 14 - Four States,...
- Magazine article from: MMWR. Morbidity and Mortality Weekly Report Anonymous November 16, 2007 700+ words
...Center laboratory of the New York State Department of Health...Chief Medical Examiner in New York City included presence...adenoviral bronchiolitis and acute respiratory distress syndrome. Investigation by the New York City Department of Health...
- Outbreak of Acute Respiratory Febrile Illness Among College Students --...
- Newspaper article from: Morbidity and Mortality Weekly Report April 13, 2001 700+ words
...Acapulco with an acute respiratory febrile illness...is defined as an acute respiratory febrile illness characterized...health departments of acute respiratory febrile illness among...Missouri, New Jersey, New York, North Carolina...
- Acute respiratory failure with diagnosis of monocytic leukemia has poor outcome.
- Newspaper article from: Drug Week August 8, 2003 700+ words
...amp; NewsRx.net) -- Acute respiratory failure can sometimes be...a study from France, "Acute respiratory failure revealing acute...monocytic leukemia presenting as acute respiratory failure. Am J Respir Crit...Society, 1740 Broadway, New York, NY 10019-4374, USA...
- Studies from O. de Zwart and co-researchers in the area of severe acute...
- Newspaper article from: Biotech Week March 25, 2009 700+ words
...efficacy for severe acute respiratory syndrome (SARS...see also Severe Acute Respiratory Syndrome Epidemiology...233 Spring Street, New York, NY 10013, USA...Netherlands, Severe Acute Respiratory Syndrome Epidemiology...
- Severe Acute Respiratory Syndrome: (SARS).(Clinical)
- Magazine article from: FOCUS: Journal for Respiratory Care & Sleep Medicine Sorbello, Joe March 22, 2003 700+ words
...Syracuse (Central/Upstate New York State). A 17 month old...pneumonia, and occasionally acute respiratory distress requiring mechanical...Clinical Description of Severe Acute Respiratory Syndrome", states the...findings of either pneumonia or acute respiratory distress ...
- Report summarizes severe acute respiratory syndrome study findings from A....
- Newspaper article from: Biotech Week July 15, 2009 700+ words
...spread of severe acute respiratory syndrome (SARS...see also Severe Acute Respiratory Syndrome). "We...of the Americas, New York, NY 10013-2473...Epidemiology, SARS, Severe Acute Respiratory Syndrome. This article...
- Social support and response to AIDS and severe acute respiratory...
- Magazine article from: Emerging Infectious Diseases Nandi, Arijit Tracy, Melissa Aiello, Allison Des Jarlais, Don C. Galea, Sandro May 1, 2008 700+ words
...towards AIDS and severe acute respiratory syndrome. Our findings...informed about severe acute respiratory syndrome (SARS...persons living in the New York City metropolitan area...were living in the New York City metropolitan area...
