Assembly of HIV-1 gag protein: a new target for antiviral therapy? (Research Report)

AUTHORS: M. Neidrig, H. Gelderblom, G. Pauli, J. Marx, A. v.Poblotzki, H. Wolf and S. Modrow. Behringwerke AG, Research Department, Marburg, Germany; Robert-Koch-Institut and AIDS-Zentrum des BGA, Berlin, Germany; Max von Pettenkofer-Institut, Munich, Germany.

According to an abstract submitted by the authors to the VIII International Conference on AIDS, held in Amsterdam, the Netherlands, July 19-24, 1992, "Objectives: Sequential overlapping gag oligopeptides of HIV-1, 22-4 amino acids long, were synthesized and tested in vitro for antiviral activity. The hypothesis has to be tested that oligopeptides representing the domains which participate in the …