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Rates of advanced breast cancer lower in The Netherlands due to mammography.
2004 NOV 4 - (NewsRx.com & NewsRx.net) -- Public health specialists in The Netherlands credit the country's breast cancer screening program with reducing incidence of advanced disease.
"The effect of the implementation of the Dutch breast cancer screening program during 1990-1997 on the incidence rates of breast cancer, particularly advanced breast cancer, was analyzed according to stage at diagnosis in seven regions, where no screening took place before 1990," said J. Fracheboud and colleagues, University Medical Center of Rotterdam.
"The Netherlands Cancer Registry provided detailed data on breast cancer incidence in 1989-1997 by tumor stage, age, and region. Annual age-adjusted incidence rates of all breast cancers and advanced cancers, defined as large tumors T2+ with lymph node and/or distant metastases, were compared with rates in 1989," the researchers explained.
Their analysis showed that "in general, breast cancer incidence rose strongly in the early 1990s, especially in the age category 50-69 years [estimated annual percentage change (EAPC) 4.25; 95% CI 1.70, 6.86]."
"The increase was mainly due to the increase in small T1 cancers and ductal carcinoma in situ," Fracheboud and team said. "However, in women aged 50-69, advanced cancer incidence rates showed a significant decline by 12.1% in 1997 compared with 1989 ...
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