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2004 NOV 4 - (NewsRx.com & NewsRx.net) -- The way a girl grows during adolescence and even in the womb may play an important, if murky, role in her risk of breast cancer later in life, a Danish study suggests.
The study of 117,000 women in Denmark found that those who were chubby at birth but tall and lean at 14 were more likely to develop the disease.
"Something very early on in life plays a role in risk of breast cancer," said lead researcher Mads Melbye, MD, professor of epidemiology at the State Serum Institute in Copenhagen.
"No one knows really what," he said, but theories include differences in levels of hormones that influence growth and genetic variations that dictate people's size.
Most studies of women have found that tall ones have an increased risk of breast cancer, that heavy ones have a higher risk of the disease after menopause, and that lean ones have a higher risk before menopause and a reduced risk after.
"We as researchers need to focus earlier in life to disentangle what really matters," Melbye said.
The study was reported in the New England Journal of Medicine.
Source: HighBeam Research, Study shows chubby babies, lean adolescents have higher breast cancer...