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Breast density, second breast cancer in women with ductal carcinoma studied.

Women's Health Weekly

| November 04, 2004 | COPYRIGHT 2004 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

2004 NOV 4 - (NewsRx.com & NewsRx.net) -- Having highly dense breasts may be associated with an increased risk of a second breast cancer among women who have had a ductal carcinoma in situ (DCIS), according to a study in the October 6 issue of the Journal of the National Cancer Institute.

Conducted by researchers from Kaiser Permanente's Division of Research, Northern California, and from the National Surgical Adjuvant Breast and Bowel Project (NSABP), this is the first study to examine the potential connection between highly dense breasts and risk of second breast cancer after DCIS.

Women with DCIS, a noninvasive cancer in which malignant-appearing cells are contained within the breast duct, have a substantially increased risk of a second breast cancer, but few predictors of this risk have been identified.

Having extensive areas of breast tissue that appear dense on mammograms has been associated with a 4- to 6-fold greater risk of a first primary breast cancer compared with women who have small or no areas of dense breast tissue.

To see if breast density was related to the risk of getting a second breast cancer after DCIS, Laurel A. Habel, PhD, Kaiser Permanente's Division of Research in Oakland, California, and colleagues studied 504 women (mostly 50 years or older) from the NSABP B-17 trial who had DCIS. The researchers examined ...

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