AccessMyLibrary provides FREE access to over 30 million articles from top publications available through your library.
Create a link to this page
Copy and paste this link tag into your Web page or blog:
Oral fluconazole safe/effective empiric treatment for neutropenic fever.
2004 NOV 4 - (NewsRx.com & NewsRx.net) -- Oral fluconazole is a safe and effective empiric treatment for persistent neutropenic fever.
According to a study from Israel, "Neutropenic patients who continue to be febrile despite adequate broad-spectrum antibacterial treatment require empirical antifungal therapy. The aim of the present study was to evaluate the safety and efficacy of oral fluconazole for empirical antifungal therapy in neutropenic patients with persistent fever.
"A prospective cohort design was used. The study sample included 250 consecutive patients with high-risk stage II, III, or responding metastatic breast cancer who received high-dose chemotherapy (HDC) with autologous peripheral blood progenitor stem cell transplantation."
"Those with neutropenic fever lasting more than 72 hours despite broad-spectrum antibacterial coverage were treated with fluconazole. Treatment was continued until fever dropped and/or neutrophil count recovered with blood cultures remaining negative," reported S.M. Stemmer and colleagues.
"Antifungal treatment was required in 173 patients (69%). There were no cases of documented deep systemic fungal infection. Two patients (
"Thirty-one patients (18%) were unable to complete the oral fluconazole protocol because of severe mucositis," said investigators, and they received intravenous fluconazole at the same dose, with similar efficacy."
"Oral fluconazole is a safe and effective alternative to ...
- Early neutropenic fever remains significant complication in RIST.
- Newspaper article from: Drug Week March 19, 2004 700+ words
...amp; NewsRx.net) -- Early neutropenic fever remains a significant complication...investigated the clinical features of neutropenic fever and infectious episodes within 30...a median duration of 9 days." "Neutropenic fever was observed in 29 patients (38...
- Which Amphotericin for Neutropenic Fever?
- Newspaper article from: Critical Care Alert May 1, 1999 700+ words
Which Amphotericin for Neutropenic Fever? Abstract & Commentary...often faced with patients with neutropenic fever. High proportions of patients...conventional treatment for persistent neutropenic fever is amphotericin B. Toxicity...
- Which Amphotericin for Neutropenic Fever?(Brief Article)(Statistical Data...
- Newspaper article from: Critical Care Alert May 1, 1999 700+ words
...more often faced with patients with neutropenic fever. High proportions of patients with...conventional treatment for persistent neutropenic fever is amphotericin B. Toxicity, especially...parameters for defining persistent neutropenic fever. Walsh and colleagues randomized...
- Correspondence.(Letter to the Editor)
- Magazine article from: Southern Medical Journal September 1, 2002 700+ words
...weeks of treatment with oral and intravenous acyclovir and oral fluconazole, she presented with increased pain and increase in the...after 3 weeks. A few weeks, later she was readmitted with neutropenic fever and sepsis and died. Actinomycosis presenting acutely...
- Chonnam National University, Department of Emergency Medicine publishes...
- Newspaper article from: Biotech Week November 18, 2009 700+ words
...results, 'Predicting the complicated neutropenic fever in the emergency department,' are...patients presented to the ED with neutropenic fever resulting from chemotherapy, with...hospitalisation. Thirty-eight episodes of neutropenic fever with complicated outcomes were identified...
- Data on antifungals discussed by researchers at Catholic University of Korea,...
- Newspaper article from: Blood Weekly February 12, 2009 700+ words
...antimicrobial usage for the management of neutropenic fever in Korea: a nationwide survey...clinical practices for the management of neutropenic fever in hematology units and hematopoietic...antibiotics in the management of neutropenic fever still accounted for a small portion...
- Research on vascular endothelial growth factor published by scientists at...
- Newspaper article from: Angiogenesis Weekly September 4, 2009 700+ words
...adult haematological patients with neutropenic fever: a comparison with C-reactive...kinetics in haematological patients with neutropenic fever." "Forty-two haematological...our haematological patients with neutropenic fever. Those with severe sepsis had higher...
- VERSICOR PLANS ANIDULAFUNGIN NDA DESPITE SECONDARY ENDPOINT MISS.
- Magazine article from: BIOWORLD Today Lorenzo, Aaron March 19, 2003 700+ words
...out of 249) and 98.8 percent of oral fluconazole patients (252 out of 255) showed...compared intravenous anidulafungin vs. oral fluconazole in about 600 esophageal candidiasis...were treated with a 200 mg dose of oral fluconazole on the first day along with an intravenous...
Source: HighBeam Research, Oral fluconazole safe/effective empiric treatment for neutropenic...