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2004 NOV 3 - (NewsRx.com & NewsRx.net) -- Influenza vaccination during pregnancy did not appear to prevent hospitalization or outpatient visits for respiratory illness in pregnant women and their infants.
"The Advisory Committee on Immunization Practices of the Centers for Disease Control and Prevention recommends influenza vaccination for women who will be in the second or third trimester of pregnancy during the influenza season. We analyzed hospital admissions with principal diagnoses of influenza or pneumonia and influenza-like illness (ILI) outpatient visits to study the effectiveness of influenza vaccine during pregnancy in protecting women and infants from influenza-related morbidity," researchers in the United States report.
"Estimates of influenza vaccine effectiveness across five flu seasons (Fall 1997 to Spring 2002) were calculated using Cox proportional hazards models for women and infant study populations in Kaiser Permanente Northern California," said Steven B. Black and colleagues at Kaiser Permanente and the Centers for Disease Control and Prevention. "Outpatient utilization outcomes included physician visits with a diagnosis of upper respiratory infection, pharyngitis, otits media, asthma, bronchial asthma, viral infection, pneumonia, fever, cough, or wheezing associated with respiratory illness. Inpatient outcomes included hospitalizations with principal diagnoses of influenza or pneumonia."
"Women who received influenza vaccine during pregnancy had the same risk for ILI visits compared with unvaccinated women, adjusting for women's age and week of delivery," reported the investigators. "When asthma visits were excluded from the outcome measure, we also found no difference in the risk of outpatient visits for vaccinated and unvaccinated women. Hospital admissions for influenza or pneumonia for women in the study population were quite rare and no women died of respiratory illness during pregnancy."
"Infants born to women who received influenza vaccination had the same risks for influenza or pneumonia admissions compared with infants ...
Source: HighBeam Research, Hospital visit prevention by influenza vaccine during pregnancy...