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Company changes name and prepares for HIV vaccine trial.

Vaccine Weekly

| November 03, 2004 | COPYRIGHT 2004 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

2004 NOV 3 - (NewsRx.com & NewsRx.net) -- Research company Merix Bioscience announced the change of its name to Argos Therapeutics, Inc. Additionally, the company stated that it is preparing for an HIV clinical trial with Argos' proprietary RNA-loaded dendritic cell vaccine.

"This change in name reflects the evolution and success of our technology platform," said Clint Dederick, Jr., chairman and CEO of Argos Therapeutics. "With our patented technology, a clinical trial underway for renal cancer and a clinical trial scheduled to begin for HIV, we've entered into an exciting new chapter for our company. We're focused on providing new therapies that will offer patients around the globe a new promise for treating diseases, and a better quality of life during the treatment."

The company said that several events brought Argos to this juncture. In March 2004, Argos (then Merix) entered into an agreement with Geron in which Argos received 5 million shares of Geron stock, valued at over $43 million. In exchange, Geron was granted the co-exclusive right to use Argos' platform technology in specific therapeutic cancer vaccines using telomerase and other defined antigens. Argos' technology obtained significant validation when Geron announced that the telomerase cancer vaccine induced vigorous immune responses without side effects in a Phase I/II clinical trial recently completed at Duke University Medical Center.

Then, in June 2004, Argos and Kirin Brewery's Pharmaceutical Division entered into a collaboration to develop and commercialize dendritic cell vaccines in the areas of cancer, infectious diseases, autoimmune disorders and transplantation. As part of the agreement, Kirin made an equity investment in Argos and each party will contribute an estimated $45 to $65 million during the first three years of the collaboration.

Additionally, Argos began a clinical trial in the same month, focusing on the treatment of renal cancer. Results for this Phase I/II ...

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Source: HighBeam Research, Company changes name and prepares for HIV vaccine trial.

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