AccessMyLibrary provides FREE access to over 30 million articles from top publications available through your library.
Create a link to this page
Copy and paste this link tag into your Web page or blog:
Interfering vaccine converts virulent infection into immunizing one.
2004 NOV 3 - (NewsRx.com & NewsRx.net) -- An interfering vaccine is a novel antiviral that converts a potentially virulent infection into one that is subclinical and immunizing.
According to a study from England, "Infection with human influenza A virus can reach cataclysmic levels, with 40 or more million deaths arising from the 1918 pandemic. Preventative and therapeutic measures have improved since that time, but new approaches are needed. Here, we describe one such new approach-the interfering vaccine, which has two activities: it prophylactically prevents influenza, and at the same time converts an otherwise lethal infection into one that is avirulent and immunizing."
"Mice treated in this way develop a solid immunity that protects them against a subsequent challenge with homologous virus, and to a lesser extent from challenge with heterologous influenza A viruses," said Simon Noble and colleagues at the University of Warwick. "The interfering vaccine comprises non-infectious, defective interfering (DI) influenza A virus. Prophylaxis is mediated directly by DI RNA, and results from interference with the replication of the infecting virus. However, interference is incomplete, and there is sufficient wild-type virus multiplication to stimulate a virus-specific natural immunity."
"As the replication mechanism is common to all influenza A viruses, an ...
- Dr. Stockmann's dilemma. (Comments).
- Magazine article from: Community Action May 19, 2003 700+ words
...people" in China results in penalties far more serious than shunning. Their hesitation allowed the spread of a virulent infection to other parts of the world and appears uncontrollable in China at this moment. It is a public health disaster...
- Dysentery
- Encyclopedia entry from: The Gale Encyclopedia of Science January 1, 2008 700+ words
...days in mild cases and up to six weeks in severe infections. Shigella dysenteriae brings about a particularly virulent infection that can be fatal within 12 to 24 hours. The patient has little or no diarrhea, but experiences delirium, convulsions...
- Hey, look, the Russians are just like us
- Newspaper article from: Chicago Sun-Times Jeff Greenfield May 31, 1988 700+ words
...summititis, compounded by a nasty strain of a Russian bug called glasnost. The combination has provoked an especially virulent infection that generally expands the number of credulous cells, and renders temporarily useless the victim's sense of...
- BioTech NEWS: Super Bug Cure?? SinoFresh Announces "Next Step" in Program to...
- Press release article from: M2 Presswire July 2, 2008 700+ words
...aureus strains) and is transferred to skin by hand contact. Under certain circumstances it can then produce a virulent infection of the skin and underlying tissues which can lead to disfigurement and sometimes death. According to Dr. John...
- Gaps yawn in X-Files' dull puzzle.
- Newspaper article from: Sunday Mercury (Birmingham, England) August 23, 1998 700+ words
...than is good for them. The interesting thing about this movie is what it tells us about American paranoia, a virulent infection that has apparently left millions believing their own Government is involved in a cover-up of the nasty truth...
- Hospital closes doors after stomach bug outbreak.
- Newspaper article from: Sunday Mercury (Birmingham, England) Palfreyman, Louise May 9, 1999 700+ words
...spread of a potentially-fatal stomach bug. Up to 36 elderly patients are thought to have been struck down with a virulent infection which causes chronic diarrhoea. They have been placed in isolation. Eleven cases of colostridium difficile have...
- Mutated HIV could serve as vaccine.
- Magazine article from: Science News Seachrist, Lisa November 11, 1995 700+ words
...A vaccine made up of a weakened form of the virus would also enter cells' DNA, creating a permanent, though less virulent, infection. Deacon maintains that scientists will need to prevent the attenuated virus from permanently infecting people before...
- Parasite pursuit: sand fly coughs up leishmania protozoan's secrets of...
- Magazine article from: Science News Seppa, N. July 24, 2004 700+ words
...along with the gel against the parasite injected with saliva. They determined that the gel results in a more virulent infection. Rogers and his coworkers also found that the active ingredient in the gel is a compound called filamentous proteophosphoglycan...
Source: HighBeam Research, Interfering vaccine converts virulent infection into immunizing one.