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Long-term insulin treatment could treble the risk of colorectal cancer (CRC) in patients with type-2 diabetes, according to an analysis of UK data.
US researchers analysed data from the UK General Practice Research Database.
The study included 24,918 patients with type-2 diabetes. Of these, 3,160 had received at least one year of insulin therapy.
Using data covering a 12-year period, the researchers found that patients who had been taking insulin for over a year were more than twice as likely to develop CRC than other type-2 diabetes patients. Further analysis revealed that CRC risk was associated with the duration of insulin treatment.