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Pioglitazone provides metabolic, reproductive benefits to PCOS patients.

Women's Health Weekly

| October 14, 2004 | COPYRIGHT 2009 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

2004 OCT 14 - (NewsRx.com & NewsRx.net) -- Pioglitazone treatment improves insulin sensitivity, hyperandrogenism, and ovulation rates in women with polycystic ovary syndrome, study results show.

"Polycystic ovary syndrome (PCOS) is characterized by hyperandrogenism, chronic anovulation, and insulin resistance; long-term consequences include diabetes mellitus type 2," wrote N. Brettenthaler and colleagues, University Women's Hospital, Basel, Switzerland.

These researchers conducted a randomized, double-blind, controlled trial to see if pioglitazone, a thiazolidinedione derivative, improved these three factors. Study subjects - 40 premenopausal women with PCOS…

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