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Plasma selenium decrease in pregnancy associated with glucose intolerance.
2004 OCT 7 - (NewsRx.com & NewsRx.net) -- According to a University of California, Davis, U.S. Department of Agriculture study, a decrease in selenium levels in plasma during pregnancy is associated with maternal glucose intolerance.
"There is an increased requirement for selenium during pregnancy, presumably for fetal growth, which manifests as decreasing maternal blood and tissue selenium concentrations. These decreases are greater in pregnant women with gestational or pre-existing diabetes," wrote W.C. Hawkes and colleagues.
For their study, they "measured selenium status and glucose tolerance between weeks 12 and 34 of gestation in 22 pregnant women."
Blood glucose increased "in response to an oral glucose challenge at 12 weeks gestation and the increase in fasting glucose during pregnancy were inversely correlated with plasma selenium concentration," according to the study.
"Women with lower plasma glutathione peroxidase activities during pregnancy also tended to have higher fasting glucose levels," the researchers reported.
They noted that "[t]hese inverse relationships between selenium status and glucose tolerance are consistent with ...
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