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Older women with heart disease, diabetes have triple the risk of heart failure.
2004 OCT 7 - (NewsRx.com & NewsRx.net) -- Postmenopausal women with heart disease have three times the risk of developing heart failure if they also have diabetes, researchers report.
In addition, diabetic women in the study who also had kidney disease or obesity, or whose diabetes was poorly controlled (fasting blood sugar levels above 300 mg/dL) had a risk of heart failure 6-10 times higher than that of women without diabetes.
Researchers analyzed records from 2391 participants in the Heart and Estrogen/Progesterone Replacement Study (HERS) to determine risk factors for developing heart failure. Previous studies recognized some significant differences in heart failure between men and women. In men, for example, a heart attack more often precedes heart failure.
The study was published in Circulation.
"In women, heart failure seems to happen often in the absence of a heart attack," said Kirsten Bibbins-Domingo, MD, PhD, lead author and an instructor in medicine, epidemiology and biostatistics at the University of California, San Francisco. "Our goal was to find out what the risk factors were in women."
In the study, 237 of the women (average age 68.3) developed heart failure during an average of 6.3 years in HERS and its follow-up. The HERS trial tested the effectiveness of hormones in preventing a second heart attack in women who had already suffered one.
The study revealed nine health factors that identify postmenopausal women with coronary artery disease who have an increased risk of developing congestive heart failure. Diabetes was the most powerful predictor of heart failure. Women who had the disease on entering HERS were 3.1 times more likely to develop heart failure than women who did not. The risk from atrial fibrillation (abnormal rapid beats in the heart's upper chambers) was nearly as great. Women with this abnormal heart rhythm were 2.9 times more likely to develop heart failure than women who did not have the condition.
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Source: HighBeam Research, Older women with heart disease, diabetes have triple the risk of...