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Defective gene thwarts cell talk, leading to breast and ovarian cancers.
2004 OCT 7 - (NewsRx.com & NewsRx.net) -- Scientists have recently discovered that the gene EDD is implicated in the development of breast and ovarian cancer.
"Cancer arises from defects in cell growth and division. We are now beginning to realize that defective cellular communication can also lead to cancer," says Rob Sutherland, director of the Cancer Research Program at the Garvan Institute in Australia.
Cells "talk" to each other in the developing embryo to coordinate themselves into higher structures like organs and blood vessels. Vigilant communication and coordination between cells is essential throughout life to maintain these structures. Part of EDD's job is to tell cells where to go.
Garvan scientists have shown that mice without EDD have the cells to make blood vessels, but they are unable to coordinate their development. Without EDD cells become confused.
Cancer is often caused by cells producing too many copies of key cancer genes. Work at Garvan has demonstrated that excess copies of the EDD gene are present in 73% of one aggressive type of ovarian cancer and that excessive amounts of the EDD protein are found in 63% of breast cancers and 39% of ovarian cancers. The ...
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- Press release article from: PR Newswire February 14, 2000 700+ words
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...contract in state history, this week's issue of Mental Health Weekly reports. Earlier this month, the Montana legislature...Magellan. Center executive director Paul Meyer told Mental Health Weekly that in the last six months, Magellan has denied $500...
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- Newspaper article from: The Brown University Child and Adolescent Behavior Letter September 1, 1995 700+ words
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The realization of a new parity law goes a long way to expanding treatment access, reducing stigma and being more cost-effective in the long run, according to longtime parity supporters, Reps. Patrick Kennedy (D-R.I.) and Jim Ramstad (R-Minn.) during exclusive interviews with MHW last week. The
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- Press release article from: PR Newswire April 27, 1999 700+ words
...EDT on Tuesday, May 18, 1999 to discuss the results. To receive the conference call telephone number, please call Jennifer Clancy at Roper Industries, Inc., at 706-369-7170. Roper Industries, Inc. is an international manufacturer of fluid handling...
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- Magazine article from: The Exceptional Parent January 1, 2003 700+ words
...8729 (707) 259-8651 (fax) * jklmatrix@aol.com CALIFORNIA, SACRAMENTO United Advocates for Children of California Jennifer Clancy 1401 El Camino Ave, Ste 340 Sacramento, CA 95815-2700 (916) 643-1534 (916) 643-1592 (fax) * jclancy@uacc4families...
Source: HighBeam Research, Defective gene thwarts cell talk, leading to breast and ovarian...