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Dense breast patterns evaluated with other risk factors of cancer.
2004 OCT 7 - (NewsRx.com & NewsRx.net) -- Cancer epidemiologists in the U.K. "studied breast parenchymal patterns and 13 other potential risk factors for breast cancer in 172 breast cancer cases and 338 age-matched controls in Singapore."
They explained, "The question of interactions between breast density and other breast cancer risk factors is of interest since it bears upon the use of density as a marker for changes in breast cancer risk."
For the study, "[d]ense breast patterns were defined as having Tabar parenchymal pattern IV or V."
S.W. Duffy and colleagues with Cancer Research UK "found significant interactions between dense patterns and ethnic group (p=0.046), and between dense patterns and number of deliveries (p=0.04)."
Of women with nondense breast patterns, non-Chinese women had lower breast cancer risk than Chinese women (odds ratio (OR) of 0.47, 95% CI 0.24, 0.88). But the opposite was the case among women with dense breast patterns: non-Chinese women had higher risk than Chinese women (OR 5.34, 95% CI 0.54, 52.51).
"Alternatively expressed," Duffy's group said, "the increased risk with dense patterns was only observed in the non-Chinese (OR 13.99, 95% CI 1.33, 146.99)."
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Source: HighBeam Research, Dense breast patterns evaluated with other risk factors of cancer.