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2004 OCT 7 - (NewsRx.com & NewsRx.net) -- Can exposure to hazardous substances at work contribute to the development of birth defects?
If so, then fathers' occupational exposures may play a more important role than mothers' exposures, suggests a study in the September 2004 Journal of Occupational and Environmental Medicine.
Led by Sin-Eng Chia of the National University of Singapore, researchers looked at whether rates of common birth defects were related to parents' occupations. The study included data on all babies born in Singapore from 1994 through 1998 - nearly 238,000 infants.
Links between occupational categories and birth defects were much more common for the fathers' jobs than for the mothers'. For example, babies whose fathers were clerical workers were 2.25 times more likely to be born with heart defects, compared to those who worked as senior officers and managers.
The risk of heart defects was also approximately doubled for babies of fathers classified as production craftsmen. The same job category was also linked to a nearly tripled risk of a group of relatively minor congenital musculoskeletal deformities.
One father's job category - plant and machine operators and assemblers - was linked to all three of the most common birth defect categories. Associations included a 2.5 times increase in heart defects, a tripled risk of musculoskeletal defects, and more than a five-fold increase in ...