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2004 OCT 7 - (NewsRx.com & NewsRx.net) -- Reproductive medicine specialists in Italy reported data from a pilot study that indicate laser-assisted intracytoplasmic sperm injection reduces damage to oocytes.
"Human oocyte survival after intracytoplasmic sperm injection (ICSI) can be compromised by abnormal oolemma breakage patterns during the penetration of the microinjection needle. We previously reported a case of repeated ICSI failures associated with abnormal oolemma breakage in which a substantial improvement and successful pregnancy were achieved by performing ICSI through a laser-drilled hole in the zona pellucida (laser-assisted ICSI), wrote L. Rienzi and colleagues.
In their current study, they compared "the efficacy of laser-assisted ICSI with that of conventional ICSI in patients whose oocytes present this particular feature."
"Oocytes treated by laser-assisted ICSI (n=140) survived better (97.9% versus 85.7%; p
"These data," they said, "show that laser-assisted ICSI is suitable for oocytes with propensity for sudden oolemma breakage during conventional ICSI. The reduction of oocyte damage with laser-assisted ICSI as compared to conventional ICSI may be useful in other clinical indications where only few oocytes are ...
Source: HighBeam Research, Laser-assisted ICSI reduces oocyte damage, pilot study shows.