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Major EU project shows "killer bacteria" more common than expected.

Vaccine Weekly

| October 06, 2004 | COPYRIGHT 2004 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

2004 OCT 6 - (NewsRx.com & NewsRx.net) -- Severe infections with Group A streptococci, sometimes called "flesh-eating killer bacteria," are considerably more common than expected in many countries.

In an EU project covering 11 countries, headed by Lund University in Sweden, it was calculated that some 1000 cases would be found over an initial 11/2-year period. Fully 5000 were identified.

Group A streptococci, GAS, can sometimes occur in the throat without the carrier noticing anything. In other cases, the bacteria can cause a benign form of strep throat or skin infection. But in some cases, partly depending on the nature of the bacterial strain, a throat or skin infection can lead to serious consequences, with chronic heart and kidney damage.

An acute GAS infection of the skin, for instance, can also dig deeper and lead to the muscles' being virtually eaten up by the bacteria. In other cases the bacteria can spread rapidly and the body's fine blood vessels start to leak fluids, which can lead to loss of blood pressure and rapid death, even in a young and previously healthy person.

"Our study has attracted a lot of attention, and we have had to turn down a number of countries that have wanted to be included in the project afterward," said Aftab Jasir from the Section for Bacteriology at Lund University. She and her colleague Claes Schalen act as coordinators of the EU study.

"Some of these 11 countries, like Italy and Romania, initially claimed that they had almost no severe GAS infections whatsoever. But once they started looking, they found a huge number of cases. In Sweden there are some 300-400 severe GAS infections every year. In relation to population size, the incidence is roughly the same in the rest of Scandinavia, Great Britain and the Czech Republic, which also have well-functioning systems for reporting these things. If we assume that this is the true incidence rate, then the enlarged EU should have 18,000-20,000 cases per year of severe ...

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