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Agent-based analysis of smallpox preparedness performed.

Vaccine Weekly

| October 06, 2004 | COPYRIGHT 2004 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

2004 OCT 6 - (NewsRx.com & NewsRx.net) -- Researchers have performed an agent-based analysis of smallpox preparedness and response policy.

According to recent research published in the JASSS - the Journal of Artificial Societies and Social Simulation, "Because conjectural 'thought experiments' can be formalized, refined, and conducted systematically using computers, computational modeling is called for in situations that demand robust quantitative study of phenomena which occur only rarely, or may never occur at all. In light of mounting concerns regarding the threats of bioterrorism in general and smallpox in specific, we developed a stochastic agent-based model, VIR-POX, in order to explore the viability of available containment measures as defenses against the spread of this infectious disease."

"We found the various vaccination and containment programs to be highly interdependent, and ascertained that these policy options vary not only in their mean effects, but also in their subordination to factors of chance or otherwise uncontrollable interference, relationships which themselves fluctuate across ranges of the counterfactual distribution," said Benjamin M. Eidelson at the Akiba Hebrew Academy and Ian Lustick at the University of Pennsylvania. "Broadly speaking, ring vaccination rivaled mass vaccination if a very substantial proportion of smallpox cases could be detected and isolated almost immediately after infection, or if residual herd immunity ...

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Source: HighBeam Research, Agent-based analysis of smallpox preparedness performed.

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