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Genetics of variations of Yersinia pestis biovars presented.
2004 OCT 6 - (NewsRx.com & NewsRx.net) -- Researchers report the genetics of metabolic variations between Yersinia pestis biovars and propose a new biovar, microtus.
"Yersinia pestis has been historically divided into three biovars: antiqua, mediaevalis, and orientalis. On the basis of this study, strains from Microtus-related plague foci are proposed to constitute a new biovar, microtus. Based on the ability to ferment glycerol and arabinose and to reduce nitrate, Y. pestis strains can be assigned to one of four biovars: antiqua (glycerol positive, arabinose positive, and nitrate positive), mediaevalis (glycerol positive, arabinose positive, and nitrate negative), orientalis (glycerol negative, arabinose positive, and nitrate positive), and microtus (glycerol-positive, arabinose-negative, and nitrate-negative)," investigators in China report.
"A 93-bp in-frame deletion in glpD gene results in the glycerol-negative characteristic of biovar orientalis strains," said Dongsheng Zhou at the Academy of Military Medical Sciences and collaborators in China. "Two kinds of point mutations in the napA gene may cause the nitrate reduction-negative characteristic in biovars mediaevalis and microtus, respectively. A 122-bp frameshift deletion in the araC gene may lead to the arabinose-negative phenotype of biovar microtus strains. Biovar microtus strains have a unique genomic profile of gene loss and pseudogene distribution, which most ...
- Yersinia pestis genotyping.(LETTERS)
- Magazine article from: Emerging Infectious Diseases Vergnaud, Gilles Raoult, Didier Drancourt, Michel Fournier, Pierre Edouard Ogata, Hiro August 1, 2005 700+ words
...an original genotyping system for Yersinia pestis based on intergenic spacer sequencing...al. Genotyping, Orientalis-like Yersinia pestis. and plague pandemics. Emerg Infect...application to the genotyping of Yersinia pestis and Bacillus anthracis. BMC Microbiol...
- Yersinia pestis virulence factors YopN, SycN and YSc crystallized.
- Newspaper article from: Proteomics Weekly December 27, 2004 700+ words
...crystallization of a ternary complex composed of Yersinia pestis virulence factors YopN, SycN and...crystallization of a ternary complex composed of Yersinia pestis virulence factors YopN, SycN and...Infection, Reductive Methylation, Yersinia pestis and Proteomics. This article was...
- Novel vaccine candidates against Yersinia pestis generated.
- Newspaper article from: Drug Week April 30, 2004 700+ words
...NewsRx.net) -- Generation of Yersinia pestis attenuated strains by signature...vaccine candidates for use against Yersinia pestis, the causative agent of plague...Infection and Immunity (Generation of Yersinia pestis attenuated strains by signature...
- Yersinia pestis Orientalis in remains of ancient plague patients.(DISPATCHES)
- Magazine article from: Emerging Infectious Diseases Drancourt, Michel Signoli, Michel Dang, La Vu Bizot, Bruno Roux, Veronique Tzortzis, Stefan Raoult, Didier February 1, 2007 700+ words
Yersinia pestis DNA was recently detected in human remains from 2 ancient plague...pandemics have been attributed to plague. The causative agent, Yersinia pestis, was discovered at the beginning of the ongoing third pandemic...
- Yersinia pestis
- Reference information from: The Mosby Medical Encyclopedia October 1, 1996 700+ words
The Mosby Medical Encyclopedia 10-01-1996 Yersinia pestis, a small bacillus that causes plague. The primary...symptoms may be a carrier, but this happens rarely. Yersinia pestis is hardy, living for long periods in infected carcasses...
- Persistence of Yersinia pestis in soil under natural conditions.(DISPATCHES)
- Magazine article from: Emerging Infectious Diseases Eisen, Rebecca J. Petersen, Jeannine M. Higgins, Charles L. Wong, David Levy, Craig E. Mead, Paul S. Schriefer, Martin E. Griffith, Kevin S. Gage, Kenneth L. Beard, C. Ben June 1, 2008 700+ words
...case investigation, we showed that the plague bacterium, Yersinia pestis, can survive for at least 24 days in contaminated soil...epizootic periods (1). Although the etiologic agent, Yersinia pestis, can be transmitted through direct contact with an infectious...
- Genotyping, orientalis-like Yersinia pestis, and plague pandemics.(Research)
- Magazine article from: Emerging Infectious Diseases Drancourt, Michel Roux, Veronique Dang, La Vu Tran-Hung, Lam Castex, Dominique Chenal-Francisque, Viviane Ogata, Hiroyuki Fournier, Pierre-Edouard Crubezy, Eric Raoult, Didier September 1, 2004 700+ words
...have been attributed to plague in the last 1,500 years. Yersinia pestis caused the third, and its DNA was found in human remains...caused by Orientalis-like strains. ********** Yersinia pestis, a group A bioterrorism agent (1), causes plague, a...
- Transferable Plasmid-Mediated Resistance to Streptomycin in a Clinical Isolate...
- Magazine article from: Emerging Infectious Diseases Guiyoule, Annie Gerbaud, Guy Buchrieser, Carmen Galimand, Marc Rahalison, Lila Chanteau, Suzanne Courvalin, Patrice Carniel, Elisabeth January 1, 2001 700+ words
...multiple antibiotics was reported in a clinical isolate of Yersinia pestis in Madagascar in 1997. We describe a second Y. pestis...first-line treatment against plague in many countries. Yersinia pestis is the causative agent of plague, a disease transmitted...
Source: HighBeam Research, Genetics of variations of Yersinia pestis biovars presented.