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2004 OCT 6 - (NewsRx.com & NewsRx.net) -- The popular hypothesis that the hepatitis B vaccine is associated with an increased risk of multiple sclerosis has been scientifically corroborated through a prospective study of patients in the United Kingdom.
Results of the study, and a related editorial, were reported in Neurology.
More than 350 million people worldwide are chronically infected with the hepatitis B virus. Of these, 65 million will die from cirrhosis or liver cancer - approximately 5000 per year in the United States. The hepatitis B vaccine, considered one of the safest vaccines ever produced, is more than 95% effective in preventing chronic hepatitis B infection, and is the first vaccine against a major human cancer.
In 1996, about 200 cases of MS (and other central nervous system demyelinating disorders) following hepatitis B vaccination were reported in France, prompting the French government to suspend routine immunization of pre-adolescents in schools. The potential link between vaccination against hepatitis B and an increased risk of MS has since been evaluated in several studies, with limited success.
Miguel Hernan, MD, DrPH, of Harvard School of Public Health, Boston, led a team of researchers in conducting a study using the General Practice Research Database (GPRD) in the U.K. The GPRD tracks many aspects of healthcare utilization, treatments and ...
Source: HighBeam Research, Vaccine may be associated with increased risk of MS.