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New assay for antigenic characterization influenza B virus developed.
2004 OCT 6 - (NewsRx.com & NewsRx.net) -- Scientists have developed a new microneutralization assay for the antigenic characterization of influenza B virus.
According to a study from Italy, "Although the hemagglutination inhibition assay is considered the 'gold standard' for antigenic characterization of influenza viruses, some limitations of this technique are well known. A new microneutralization assay, as a tool for antigenic characterization of influenza B viruses, has been standardized and its performance evaluated in comparison with the hemagglutination inhibition test in the light of molecular characterization of the hemagglutinin. Twelve B viruses belonging to the two lineages and the four sub-lineages discriminated by phylogenetic analysis of HA were tested."
"The microneutralization assay clearly distinguishes viruses belonging to different lineages and, in addition, discriminates strains belonging to different sub-lineages that are poorly or not discriminated using the hemagglutination inhibition test," said Filippo Ansaldi and colleagues at the University of Genoa. "This new microneutralization assay could provide a useful tool for antigenic characterization of ...
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Source: HighBeam Research, New assay for antigenic characterization influenza B virus developed.