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MAdCAM-1-expressing sacral lymph nodes provide site for immunity.
2004 OCT 6 - (NewsRx.com & NewsRx.net) -- The MAdCAM-1-expressing sacral lymph nodes in lymphotoxin beta-deficient mice provide a site for immune generation following vaginal herpes simplex virus-2 infection.
According to a study from the United States, "The members of the lymphotoxin (LT) family of molecules play a critical role in lymphoid organogenesis. Whereas LTalpha-deficient mice lack all lymph nodes and Peyer's patches, mice deficient in LT,6 retain mesenteric lymph nodes and cervical lymph nodes, suggesting that an LTbeta-independent pathway exists for the generation of mucosal lymph nodes. In this study, we describe the presence of a lymph node in LTbeta-deficient mice responsible for draining the genital mucosa."
"In the majority of LTbeta-deficient mice, a lymph node was found near the iliac artery, slightly misplaced from the site of the sacral lymph node in wild-type mice," stated Kelly A. Soderberg and colleagues at Yale University. "The sacral lymph node of the LTbeta-deficient mice, as well as that of the wild-type mice, expressed the mucosal addressin cell adhesion molecule-1 similar to the mesenteric lymph node. Following intravaginal infection with HSV type 2, activated dendritic cells capable of stimulating a Th1 response were found in this sacral lymph node."
"Furthermore, normal HSV-2-specific IgG responses were generated in the ...
- MAdCAM-1-expressing sacral lymph nodes provide site for immunity.
- Magazine article from: Women's Health Weekly October 7, 2004 700+ words
...misplaced from the site of the sacral lymph node in wild-type mice," stated...colleagues at Yale University. "The sacral lymph node of the LTbeta-deficient mice...response were found in this sacral lymph node." "Furthermore, normal HSV...
- Sentinel Lymph Node Biopsy for Breast Cancer.
- Magazine article from: AORN Journal KELLAR, STEPHANIE J. August 1, 2001 700+ words
...heralded a new era in surgery. Sentinel lymph node biopsy is one of the new technologies...utilization.(1) WHAT IS SENTINEL LYMPH NODE BIOPSY? The lymphatic system disseminates...region. The sentinel node is the first lymph node in a regional lymphatic basin to receive...
- Sentinel lymph node biopsy using lymphoscintigraphy.
- Magazine article from: AORN Journal Hader, Deborah J. Moss, Kevin V. Geier, Noelle October 1, 1998 700+ words
...interdisciplinary approach. Sentinel lymph node biopsy commonly is used for patients...There are other applications for sentinel lymph node biopsy, but this article focuses on...embolize, and are carried toward a lymph node, where they become trapped.(2) Lymph...
- The number of lymph node metastases predicts cure after thyroid cancer surgery.
- Newspaper article from: Biotech Week July 2, 2003 700+ words
...amp; NewsRx.net) -- The number of lymph node metastases predicts cure after thyroid...thyroidectomy with central and bilateral lymph node dissection," scientists writing in...Metabolism report. "At histology, lymph node metastases were found in 55% of patients...
- Inadequate Lymph Node Resections in Colorectal Cancer Surgery.(Clinical report)
- Newspaper article from: Clinical Oncology Alert March 1, 2005 700+ words
Inadequate Lymph Node Resections in Colorectal Cancer Surgery...variability. The implications of inadequate lymph node resection are considerable with regard...Cancer Inst. 2005;97:219-225. Lymph node status is the strongest predictor of...
- Lymphatic Mapping and Sentinel Lymph Node Biopsy.
- Magazine article from: AORN Journal FOCHT, SANDRA L. April 1, 1999 700+ words
...reducing the morbidily of elective lymph node dissections and rendering them unnecessary...intraoperative lymphatic mapping and sentinel lymph node biopsy using gamma detector probes...drainage from the primary site to possible lymph node basins and selective lymph node ...
- Lymph Node Biopsy
- Encyclopedia entry from: Gale Encyclopedia of Medicine, 3rd ed. Davidson, Tish January 1, 2006 700+ words
Lymph Node Biopsy Definition A lymph node biopsy is a procedure in which all or part of a lymph node is removed and examined to determine if there is cancer within the node. Purpose The lymph system is the body's primary defense against infection...
- Extended lymph node dissection fails to increase survival.
- Newspaper article from: Gastroenterology Week May 3, 2004 700+ words
...com & NewsRx.net) -- Extended lymph node dissection - a treatment for gastric...randomized trial of limited and extended lymph node dissection among this population. Gastric...community over the benefit of extended lymph node dissection among gastric cancer patients...
