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Yeast-based immunotherapy causes mutation-selective tumor remission.
2004 OCT 6 - (NewsRx.com & NewsRx.net) -- Ras-targeted, whole yeast-based immunotherapy resulted in mutation-selective tumor remission.
"Activating mutations in Ras oncoproteins represent attractive targets for cancer immunotherapy, but few vectors capable of generating immune responses required for tumor killing without vector neutralization have been described. Whole recombinant yeast heterologously expressing mammalian mutant Ras proteins were used to immunize mice in a carcinogen-induced lung tumor model," scientists in the United States report.
"Therapeutic immunization with the whole recombinant yeast caused complete regression of established Ras mutation-bearing lung tumors in a dose-dependent, antigen-specific manner," said Yingnian Lu and colleagues at GlobeImmune Inc. and the University of Colorado. "In combination with the genomic sequencing of tumors in patients, the yeast-based ...
- Yeast-based immunotherapy causes mutation-selective tumor remission.
- Newspaper article from: Health & Medicine Week October 4, 2004 700+ words
...resulted in mutation-selective tumor remission. "Activating...published their study in Cancer Research (Mutation-selective tumor remission with Ras-targeted...information for the journal Cancer Research is: American Association...
- Spectrum Pharmaceuticals Announces the Presentation of New Preclinical Data on...
- Press release article from: PR Newswire April 13, 2006 700+ words
...announced the presentation of new preclinical data on SPI-1620 at the 97th Annual Meeting of the American Association for Cancer Research (AACR) in Washington, DC, earlier this month. A poster entitled "IRL-1620, a tumor selective vasodilator, enhances...
- Protamine Induces Selective Tumor Thrombosis.
- Newspaper article from: Biotech Week August 22, 2001 700+ words
2001 AUG 22 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - The peptide protamine can be used to reduce blood flow in breast cancer and other adenocarcinoma tumors by provoking thrombus formation, according to pathologists in the United States. "Adenocarcinomas in rats
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- Press release article from: M2 Presswire October 31, 2006 700+ words
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- The American Association for Cancer Research Now Accepting Nominations For The...
- Press release article from: PR Newswire July 1, 2002 700+ words
...PHILADELPHIA -- The American Association for Cancer Research (AACR) is now accepting nominations...recognize seminal basic and translational cancer research discoveries at the cutting edge of...extraordinary basic and translational cancer research advances and whose scientific ...
- First comprehensive map of cancer research in the U.K. is unveiled.
- Newspaper article from: Cancer Weekly November 19, 2002 700+ words
...first detailed analysis of cancer research in the United Kingdom shows...published by the U.K. National Cancer Research Institute (NCRI) is the first...give a definitive breakdown of cancer research funded by the government and...
