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Heat shock proteins reviewed.
2004 OCT 6 - (NewsRx.com & NewsRx.net) -- Researchers review heat shock proteins in a recent issue of Immunology Letters.
"The contribution of major histocompatibility complex (MHC) I and II to the adaptive immune response has been well documented. In 1996, Peter Doherty and Rolf Zinkernagel were awarded the Nobel Prize, for their fundamental observations concerning the genetic elements involved in specific antigen (Ag) recognition. These elements encode molecules that present self and non-self peptide fragments to both CD4+ and CD8+ cytolytic T lymphocytes (CTL)," investigators in Singapore report.
"The recognition by Srivastava and coworkers that heat shock proteins (HSPs) might also present antigen in chemically induced sarcomas brought about many new questions concerning the central dogma of antigen processing and presentation," said Charles A. Gullo and Gerrard Teoh at Singapore Health Services (SingHealth). "HSPs, in particular glucose-regulated peptide 94 (GRP94), HSP70 and to a lesser extent HSP90, bind peptides that are immunogenic in vitro and in vivo. There is mounting evidence that these HSP-peptide complexes provide alternative antigen-specific recognition in many systems."
"Whether a separate genetic program evolved in ...
- Heat shock proteins reviewed.
- Newspaper article from: Cancer Vaccine Week October 4, 2004 700+ words
...Researchers review heat shock proteins in a recent issue of Immunology Letters. "The contribution...their study in Immunology Letters (Heat shock proteins: to present or...of the journal Immunology Letters can be contacted...
- A raison d'etre for heat-shock proteins.
- Magazine article from: Science News Vaughan, Christopher May 7, 1988 700+ words
A raison d'etre for heat-shock proteins Cells of all organisms respond to heat or other stresses by making complex molecules called heat-shock proteins. Ohter heat-shock proteins exist in unstressed cells and seem to play a role...
- Nature's remedy for stressed-out plants. (heat-shock proteins found in field...
- Magazine article from: Science News January 6, 1996 700+ words
...generate hardy molecules called heat shock proteins that not only resist stress but also...for example, the genes for heat shock proteins turn on, churning out the protective...molecules until the stress subsides. Heat shock proteins appear to work by binding to distorted...
- Heat shock proteins protect retina.
- Press release article from: PR Newswire September 29, 1988 700+ words
...30 P.M., SEPT. 29, 1988/ HEAT SHOCK PROTEINS PROTECT RETINA /ADVANCE/ WINSTON...Sept. 29 /PRNewswire/ -- Heat-shock proteins, part of the body's natural defenses...in retinal synthesis of three heat-shock proteins when rats were exposed to a fever of...
- Heat shock proteins may protect retina from damage.
- Press release article from: PR Newswire May 24, 1988 700+ words
HEAT SHOCK PROTEINS MAY PROTECT RETINA FROM DAMAGE WINSTON...can stimulate the formation of heat shock proteins in rats by raising the rat's body...survive better." Tytell said the heat shock proteins are produced by a wide variety of...
- Heat shock proteins; new research.(Brief article)(Book review)
- Magazine article from: SciTech Book News March 1, 2009 700+ words
9781604566413 Heat shock proteins; new research. Ed. by Emma...research in the field of heat shock proteins (HSP), groups of proteins whose...A sampling of topics: heat shock proteins as possible anti-HIV agents...
- RESEARCHERS VACCINATE AGAINST CANCER USING HEAT SHOCK...
- Newspaper article from: Rocky Mountain News (Denver, CO) October 3, 1997 700+ words
...School of Medicine used heat shock proteins from the cancer to activate...immune system against it. Heat shock proteins have a number of roles, including...noted research that showed heat shock proteins could be used against cancers...
- Heat-shock proteins and host-pathogen interactions reviewed.
- Newspaper article from: Immunotherapy Weekly October 6, 2004 700+ words
...net) -- Scientists review heat-shock proteins and the host-pathogen interaction...Current Opinion in Immunology. "Heat-shock proteins (HSPs) are expressed at high levels...survival. Both host and pathogen heat-shock proteins contribute to immunity by receptor...
