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HIV vaccine combination safe and immunogenic in HIV-negative adults.
2004 OCT 6 - (NewsRx.com & NewsRx.net) -- An HIV subtype B and E prime-boost vaccine combination was safe and immunogenic in HIV-negative Thai adults.
"ALVAC-HIV (vCP1521) and AIDSVAX B/E were evaluated in a phase 1/2 trial of human immunodeficiency virus (HIV)-negative Thai adults. Of 133 volunteers enrolled, 122 completed the trial. There were no serious vaccine-related adverse events, nor were there intercurrent HIV infections. Lymphoproliferative responses to glycoprotein 120 E were induced in 63% of the volunteers, and HIV-specific CD8 cytotoxic T lymphocyte responses were induced in 24%," an international team of investigators reports.
"Antibody responses increased in frequency and magnitude in association with the dose level of AIDSVAX B/E," said Sorachai Nitayaphan at the Armed Forces Research Institute of Medical Sciences in Bangkok and fellow members of the Thai AIDS Vaccine Evaluation Group. "Binding and neutralizing antibodies to the MN strain were induced in 100% and 98%, respectively, of the volunteers receiving 600 mcg of AIDSVAX B/E, and such antibodies to E strains were induced in 96% and 71%, ...
- HIV vaccine combination safe and immunogenic in HIV-negative adults.
- Newspaper article from: Biotech Week October 6, 2004 700+ words
...amp; NewsRx.net) -- An HIV subtype B and E prime-boost vaccine combination was safe and immunogenic in HIV-negative Thai adults. "ALVAC...subtype B and E prime-boost vaccine combination in HIV-negative Thai adults. J Infec...
- Murine Study Indicates Estrogen and Vaccine Combination May Prevent...
- Newspaper article from: Immunotherapy Weekly May 28, 2000 700+ words
...disease. Vaccine alone prevented the disorder more effectively in males than in females, and only the estrogen-vaccine combination completely protected females. In addition to boosting numbers of regulatory T cells, the researchers found combination...
- Murine Study Indicates Estrogen and Vaccine Combination May Prevent...
- Newspaper article from: Vaccine Weekly May 24, 2000 700+ words
...disease. Vaccine alone prevented the disorder more effectively in males than in females, and only the estrogen-vaccine combination completely protected females. In addition to boosting numbers of regulatory T cells, the researchers found combination...
- The Induction of Immunologic Memory After Vaccination With Haemophilus...
- Newspaper article from: Vaccine Weekly September 13, 1999 700+ words
...Haemophilus influenzae Type b Conjugate and Acellular Pertussis-Containing Diphtheria, Tetanus, and Pertussis Vaccine Combination." Journal of Infectious Diseases, August 1999;180(2):538-541. (CW HENDERSON PUBLISHER www.newsfile...
- Vaccine Combination Rejects Brain Tumor Establishment In Rodents.(Brief Article)
- Newspaper article from: Vaccine Weekly February 20, 2002 700+ words
2002 FEB 20 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, senior medical writer - Using a combination of cytokine-based gene therapy and tumor cell vaccination, medical investigators have been able to produce immunity against brain tumors in rats. The strategy of using a combination of
- Vaccine Combination Rejects Brain Tumor Establishment In Rodents.
- Newspaper article from: Pain & Central Nervous System Week February 18, 2002 700+ words
2002 FEB 18 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, senior medical writer - Using a combination of cytokine-based gene therapy and tumor cell vaccination, medical investigators have been able to produce immunity against brain tumors in rats. The strategy of using a combination of
- Phase II study results of vaccine combination released.
- Newspaper article from: Vaccine Weekly May 14, 2003 700+ words
2003 MAY 14 - (NewsRx.com & NewsRx.net) -- Xenova Group plc (NASDAQ: XNVA; London Stock Exchange: XEN) has announced the results of an open label, physician-sponsored Phase II "prime-boost" study, targeting the treatment of human papillomavirus (HPV) associated ano-genital intraepithelial
- Combination HIV Vaccine Induces Diverse Immune Responses.(Statistical Data...
- Newspaper article from: Vaccine Weekly August 9, 1999 700+ words
...safety of the vaccine combination in individuals...infected with HIV, more than...receiving the vaccine combination, have developed...can inhibit HIV in a laboratory...whether the vaccine combination can protect against HIV or AIDS...