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Messenger RNA-based vaccines reviewed.

Vaccine Weekly

| October 06, 2004 | COPYRIGHT 2004 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

2004 OCT 6 - (NewsRx.com & NewsRx.net) -- Scientists review messenger RNA-based vaccines in a recent issue of Expert Opinion on Biological Therapy.

According to a study from Germany, "RNA is the only molecule known to recapitulate all biochemical functions of life: definition, control, and transmission of genetic information, creation of defined three-dimensional structures, enzymatic activities, and storage of energy. Because of its versatility and thanks to several recent scientific breakthroughs, RNA became the focus of intense research in molecular medicine at the beginning of the millennium. In particular, mRNA can be seen as a safe and efficient alternative to protein-, recombinant virus- or DNA-based therapies in the field of vaccination."

"This review summarizes the most remarkable advances in this area and presents the advantages and limits of the five different mRNA-based vaccination methods," said Steve Pascolo at CureVac GmbH. "The paper will ...

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Source: HighBeam Research, Messenger RNA-based vaccines reviewed.

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