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HPV type 16 L1 virus-like particle vaccine may prevent infection.

Vaccine Weekly

| October 06, 2004 | COPYRIGHT 2004 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

2004 OCT 6 - (NewsRx.com & NewsRx.net) -- A human papillomavirus (HPV) type 16 L1 virus-like particle vaccine shows promise for protection against HPV16 infection.

"A post hoc analysis was performed using combined data from two Phase I tolerability/immunogenicity studies of monovalent human papillomavirus type 11 (HPV11) or HPV16L1 virus-like particle (VLP) vaccines. The goal was to determine if the HPV16L1 VLP vaccine protected against HPV16 infection. Vaccine or placebo was given at 0, 2 and 6 months. HPV16 infection was defined by positive polymerase chain reaction (PCR) results following vaccination," scientists in the United States report.

"The incidence of HPV infection was observed to be 0 cases per 100 person-years at risk in the vaccine group, and 5 cases per 100 person-years at risk in the control group," stated Darron R. Brown at Indiana University and collaborators throughout the U.S. "These results support the institution of larger efficacy ...

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Source: HighBeam Research, HPV type 16 L1 virus-like particle vaccine may prevent infection.

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