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Strategies to improve dendritic cell cancer immunotherapy outlined.
2004 OCT 6 - (NewsRx.com & NewsRx.net) -- Researchers outline strategies to improve dendritic cell-based immunotherapy against cancer in a recent issue of the Yonsei Medical Journal.
"Dendritic cells (DCs) play a pivotal role in T cell-mediated immunity and have been shown to induce strong antitumor immune responses in vitro and in vivo. Various approaches utilizing different vaccine cell formats, cell numbers, vaccination schedule, site of vaccination and maturation stages of DCs were investigated worldwide. While clinical trials have demonstrated the safety of such strategies, the clinical outcome was less than expected in most cases," scientists in South Korea report.
"This is due to in part host immunodeficiency imposed by tumors and immuno-editing of tumor cells," said Si Young Song and Han-Soo Kim at Yonsei University. "To overcome these obstacles, new approaches to improve DC-mediated immunotherapeutic strategies are under investigation. First, functional enhancement of monocyte-derived DCs can be generated with using flt3-ligand (FL). Second, diverse antigenic determinants from heat shock-treated tumor cells may improve the immunogenicity of DC-based vaccines. Third, inclusion of ex vivo expanded NK/NKT cells in DC-based vaccines could be beneficial since the bidirectional interaction of these two cell types are known to enhance NK cell ...
- South Korea Salmonella enterica outbreak linked to infant formula.
- Newspaper article from: Health & Medicine Week May 3, 2004 700+ words
...their study in the Yonsei Medical Journal (Salmonella enterica...200822, Gangwon-do, South Korea. The publisher of the Yonsei Medical Journal can be contacted at...Ku, Seoul 120-752, South Korea. The information in this...
- Study data from Eulji Hospital, Department of Pediatrics provide new insights...
- Magazine article from: Women's Health Weekly October 2, 2008 700+ words
...study in Yonsei Medical Journal (Risk factors...term babies in South Korea. Yonsei Medical Journal, 2008;49(4...for the Yonsei Medical Journal is: Yonsei University...Seoul 120-752, South Korea. Keywords: Korea...
- South Korea Nuclear Power Market Analysis and Forecasts to 2015.
- Press release article from: Business Wire February 24, 2009 700+ words
...report is available in its catalogue. South Korea Nuclear Power Market Analysis and Forecasts...www.reportlinker.com/p0102254/South-Korea-Nuclear-Power-Market-Analysis-and-Forecasts-to-2015.html South Korea Nuclear Power Market Analysis and Forecasts...
- South Korea's growing soft power gives it a larger role in global governance.
- Newspaper article from: The Daily Star (Beirut, Lebanon) November 11, 2009 700+ words
...Asian Nations met in Thailand last month, South Korea was an important presence. Quietly, South Korea has moved away from being defined by its...Asian Nations met in Thailand last month, South Korea was an important presence. Quietly...
- South Korea's nuclear surprise: as more and more countries adopt the IAEA's...
- Magazine article from: Bulletin of the Atomic Scientists Kang, Jungmin Hayes, Peter Bin, Li Suzuki, Tatsujiro Tanter, Richard January 1, 2005 700+ words
...INTERNATIONAL Atomic Energy Agency (IAEA), South Korea publicly disclosed its past secret nuclear...these activities to the IAEA in Vienna. South Korea's surprise reappearance on the list...years after they had been suppressed by South Korea's secretive nuclear establishment...
- SOUTH KOREA'S PER CAPITA GDP OVERTAKES TAIWAN'S FOR FIRST TIME.
- News wire article from: AsiaPulse News April 6, 2006 700+ words
...The economic race between Taiwan and South Korea took a new twist in 2005, with South Korea overtaking Taiwan in per capita gross domestic...said the government should not overlook South Korea's rapid economic growth and should instead...
- South Korea Draws Largest TV Audiences for June 10-16, According to Nielsen...
- Press release article from: Business Wire June 28, 2002 700+ words
Business Editors South Korea may have been eliminated from World...defeat Portugal, 1-0, at Incheon South Korea, June 14, making it the most...Nielsen's 18 measured markets. In South Korea alone, a combined audience of nearly...
- SOUTH KOREA, THE BARRIER ECONOMY
- Newspaper article from: The Boston Globe Tom Ashbrook, Globe Staff March 29, 1987 700+ words
...United States last year. After July 1, South Korea -- the country that brings you Hyundai...trade warriors in the US Congress, South Korea is throwing in an extra, opening its...For decades, no one much cared about South Korea's array of clam-tight import restrictions...
