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Microarrays suitable for analyzing X-linked gene expression.

Health & Medicine Week

| September 20, 2004 | COPYRIGHT 2009 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

2004 SEP 20 - (NewsRx.com & NewsRx.net) -- Microarray analysis can be used to evaluate inactivation of X-linked genes.

"Dosage compensation in mammalian females is achieved by the random inactivation of one X chromosome early in development; however, inactivation is not complete," scientists in England explained. "In addition to a majority of pseudoautosomal loci, there are genes that are expressed from both the active and the inactive X chromosomes, and which are interspersed among other genes subject to regular dosage compensation."

"The patterns of X-linked gene expression in different tissues are of great significance for interpreting their impact on sex…

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Source: HighBeam Research, Microarrays suitable for analyzing X-linked gene expression.

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