AccessMyLibrary provides FREE access to millions of articles from top publications available through your library.
Create a link to this page
Copy and paste this link tag into your Web page or blog:
Susceptibility of HIV-1 isolates to zidovudine - correlation between widely applicable culture test and PCR analysis. (polymerase chain reaction) (Periodical Report)
SOURCE: Journal of Acquired Immune Deficiency Syndromes, April 1992;5(4):359-364.
The polymerase chain reaction (PCR) technique can be used to determine the susceptibility of virtually any patient isolate of HIV-1 to zidovudine (AZT), a French study indicates.
Pitie-Salpetriere Hospital researchers Magdelena Jung, Henri Agut, and colleagues evaluated the ability of PCR to predict AZT susceptibility in 13 HIV-1 isolates obtained via coculture with peripheral blood lymphocytes (PBL).
In vitro tests established that seven virus isolates from untreated subjects and four of six isolates from AZT-treated subjects were susceptible to AZT. The …
-
- HIV may develop resistance preferentially to azidothymidine (AZT) as compared...
-
Newspaper article from: AIDS Weekly
Shirasaka, Takuma Yarchoan, R. Husson, R. Shimada, T. Wyvill, K.M. Broder, S. Mitsuya, H.
July 29, 1991
700+ words
-
- Simple test could help accuracy in deciding when HIV-infected persons are...
-
Newspaper article from: AIDS Weekly
June 14, 1993
700+ words
-
- Researchers announce results of combined HIV therapy. (3TC plus AZT)
-
Newspaper article from: AIDS Weekly
December 5, 1994
700+ words
-
- Experimental AIDS compound effective in lab tests against AZT- and...
-
Newspaper article from: AIDS Weekly
November 15, 1993
700+ words
-
- HIV-infected patients on AZT benefit from switch to ddI, multi-center study...
-
Newspaper article from: AIDS Weekly
September 7, 1992
700+ words
