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Culture systems improve the study of gene function in inaccessible tissue.
2004 SEP 18 - (NewsRx.com & NewsRx.net) -- Culture systems improve the study of gene function in inaccessible tissue.
"The development of an organ culture system for growing prenatal intercostal muscle in vitro and its use to study gene function is described. Fetal skeletal muscle is relatively inaccessible during the key stages of its development, and this method enables DNA transfections and other manipulations to be carried out. The system allows cell proliferation and differentiation to continue and also maintains the morphology and fiber types of developing muscle," scientists writing in the journal Muscle & Nerve report.
"Gene transfer into cultured embryonic intercostal muscle was achieved by square-pulse electroporation of intact pieces of tissue. Expression of a marker gene green fluorescent protein (GFP) was found within 5 hours and maintained for 2 days in muscle fibers and cells," wrote S.M.P. Cardoso and colleagues, University of Nottingham Hospital, Queens Medical ...
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- Isis Pharmaceuticals' GeneTrove Division Introduces Human Gene Function...
- Press release article from: PR Newswire August 9, 2001 700+ words
...antisense technology-based Human Gene Function Database, the first database that...Boston, August 13-17. The Human Gene Function Database will allow partners to ask...This unique ability to conduct human gene function hypothesis testing will help guide...
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- Press release article from: PR Newswire September 6, 2000 700+ words
...involving Deltagen's DeltaBase(TM) gene function database and Deltagen's DeltaSelect...delivered to Glaxo Wellcome, containing gene function information for potential new drug...s DeltaBase database for mammalian gene function. Glaxo Wellcome will have non-exclusive...
Source: HighBeam Research, Culture systems improve the study of gene function in inaccessible...