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Role of HTLV-I Tax and NFKB in Transgenic Tumor
AUTHORS: M.I. Nerenberg and I. Kitajima. Department of Neuropharmacology, The Scripps Research Institute, La Jolla, California.
According to an abstract submitted by the authors to a joint meeting of the Association for American Physicians, American Society for Clinical Investigation and American Federation for Clinical Research, held May 1-4, 1992, in Baltimore, Maryland, "Human T-Lymphotropic Virus type I (HTLV-I) is the cause of an adult T-cell leukemia found in endemic regions. Tax, the transcriptional transactivator encoded by this virus, is a pleiomorphic activator of cellular genes and has been …