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GTx collaborates to develop a diagnostic test to detect high-grade PIN.
2004 SEP 2 - (NewsRx.com & NewsRx.net) -- GTx, Inc., (GTXI), a biopharmaceutical company dedicated to the discovery, development, and commercialization of therapeutics primarily related to the treatment of serious men's health conditions, announced it has entered into a collaboration with Tessera, Inc.
Under the terms of the agreement GTx will provide clinical samples from its completed phase IIb clinical trial program which evaluated ACAPODENE (toremifene citrate) for the reduction of the incidence of prostate cancer in men with high-grade prostatic intraepithelial neoplasia (PIN), a premalignant lesion that has the potential to progress to prostate cancer. ACAPODENE is a nonsteroidal selective estrogen receptor modulator that appears to block the estrogen's unwanted actions on the prostate.
The collaboration will focus on the development of a commercial blood or urine test which could detect high-grade PIN in the millions of men who unknowingly harbor this precancerous lesion of the prostate or who may develop prostate cancer.
"Currently, there are an estimated 9.4 million men in the U.S. alone who unknowingly harbor high-grade PIN, but on average, only 115,000 of these men will be diagnosed each year," said Mitchell Steiner, MD, CEO of GTx. "When a blood or ...
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...000 new cases of prostate cancer. High grade PIN is found in an...found to have high grade PIN are at high risk of prostate cancer with up to 37...the incidence of prostate cancer in men with high grade PIN. Results from...
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...disease. "High grade PIN is in the direct...causal pathway to prostate cancer," stated Mitchell...new cases of prostate cancer. High grade PIN is found in...to have high grade PIN are at high risk of prostate cancer with up to 37...
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- Press release article from: PR Newswire June 2, 2004 700+ words
...at high risk for prostate cancer and high grade PIN. The primary endpoint...the incidence of prostate cancer. This is the largest...men who have high grade PIN are indeed high-risk patients for prostate cancer with 31% of the...
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- Press release article from: PR Newswire July 16, 2004 700+ words
...that high grade PIN patients...developing prostate cancer. The study...high grade PIN patients...risk for prostate cancer." Dr...development of prostate cancer in a patient...with high grade PIN when we know...
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- Press release article from: PR Newswire July 27, 2004 700+ words
...000 new cases of prostate cancer. High grade PIN is found in an...found to have high grade PIN are at high risk of prostate cancer with up to 37...diagnosed with prostate cancer within 1 year. High grade PIN clinical development...
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- Press release article from: PR Newswire June 15, 2004 700+ words
...test from blood or urine to detect high grade PIN and/or prostate cancer. "High grade PIN identifies patients who are at high...to detect over 230,000 new cases of prostate cancer. High grade PIN is found in an average of 9% of prostate...
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...deprivation therapy for prostate cancer." Presenter: MR Smith...deprivation therapy for advanced prostate cancer, and second, a pivotal...for the prevention of prostate cancer in high risk men with high grade PIN. GTx also is developing...
- GTx, Inc., collaborates to develop a diagnostic test for high grade PIN.
- Newspaper article from: Medical Devices & Surgical Technology Week July 18, 2004 700+ words
...test from blood or urine to detect high grade PIN and/or prostate cancer. "High grade PIN identifies patients who are at high...our novel biomarkers in detecting high grade PIN and/or prostate cancer," said Patrick Plewman, CEO of diaDexus...
