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Gender differences exist in cytokine secretion from cytomegalovirus infection.
2004 SEP 2 - (NewsRx.com & NewsRx.net) -- Gender differences exist in cytokine secretion resulting from cytomegalovirus infection.
According to recent research from the United States, "Cell-mediated memory immune responses to viral antigens are important for protection against viruses causing persistent or acute infections. This study compared the cytokine profile of memory T-helper cells specific for cytomegalovirus (CMV) in healthy CMV-seropositive men and women. The cytokine response reflected T(H)1 bias, with dominant secretion of interferon (IFN)-gamma along with moderate levels of tumor necrosis factor-alpha, interleukin (IL)-10, and IL-2."
"Analyzed by gender, women had higher and significant spontaneous release of IFN-gamma and CMV-specific IL-2 secretion," reported Maria C. Villacres and colleagues at the City of Hope National Medical Center. "Similar analysis with herpes simplex virus-1 showed a trend toward higher cytokine responsiveness in women, but the differences were not statistically significant. In contrast, men had statistically significant higher influenza virus-specific tumor necrosis factor-a secretion. IL-4 and IL-5, both Th2 cytokines, were low for all three viruses. The results show a ...
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Source: HighBeam Research, Gender differences exist in cytokine secretion from cytomegalovirus...