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Advances made in diagnosis of maternal CMV infection.
2004 SEP 2 - (NewsRx.com & NewsRx.net) -- According to a study from Italy, "In most European countries, pregnant women are tested for cytomegalovirus (CMV) during the first trimester of pregnancy.
"Within the last 5 years, European laboratories have made significant progress in solving diagnostic problems linked to infection in pregnancy. With advances in CMV serology, the presence of anti-CMV immunoglobulin (Ig) M detected by a screening test such as enzyme immunoassay, can be confirmed by blot, identifying pregnant women undergoing an active or recent infection."
"Furthermore, primary infections that were proven if a seroconversion was observed or suspected in the presence of IgM can now be readily diagnosed by disclosing the presence of anti-CMV low avidity in IgM-positive mothers, greatly reducing the number of women who should be considered at risk of transmitting the virus," wrote T. Lazzarotto and colleagues, University of Bologna.
"Virologic maternal tests are not enough to diagnose a recent primary maternal CMV infection and the detection or quantification of CMV in maternal blood does not seem to be associated with a higher risk ...
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Source: HighBeam Research, Advances made in diagnosis of maternal CMV infection.