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Biosynthesis of marmoset proteins occurs in oocytes and follicle cells.
2004 SEP 2 - (NewsRx.com & NewsRx.net) -- Researchers have gathered in formation about the localization and synthesis of zona pellucida proteins in the marmoset monkey (Callithrix jacchus) ovary.
According to recent research published in the journal Molecular Human Reproduction, "In most species, the zona pellucida (ZP), an extracellular matrix surrounding the mammalian oocyte, is composed of three glycoproteins: ZPA, ZPB and ZPC.
"Based mainly on results with mice, the site of zona pellucida biosynthesis has been suggested to be exclusively in the oocyte cytoplasm. However, evidence is accumulating that among various species cumulus/granulosa cells may be involved."
K. Bogner and colleagues of the University of Giessen wrote,"Because knowledge of ZP biosynthesis in primates is lacking, we used the common marmoset (Callithrix jacchus) to acquire information about the localization and the site of synthesis of ZP proteins in this species. Using antibodies against synthetic ZPA and ZPC peptides, immunoreactivity was found in the marmoset ZP and in surrounding cumulus cells."
"Interestingly, the amounts of ZPA and ZPC proteins expressed appeared to differ depending on the stage of folliculogenesis. RT-PCR analysis of mRNA from marmoset oocytes and ...
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